电视胸腹腔镜联合颈部三切口在食管癌患者中的应用效果

Abstract
Figure/Table
References (25)
Related Citation (15)

Download: PDF (552 KB) HTML (1 KB)
Export: BibTeX | EndNote (RIS)

Abstract Objective To investigate the application effect of video assisted thoracoscopy combined with three incisions of neck in the treatment of esophageal cancer. Methods A total of 124 patients diagnosed with esophageal cancer in Rugao Hospital Affiliated to Nantong University from April 2015 to July 2017 were selected as the study subjects. The patients were divided into observation group and control group by random number table method, with 62 cases in each group. The control group was treated with traditional open surgery, and the observation group was treated with video assisted thoracoscopy combined with three incisions of neck. Surgery related indexes were compared between the two groups. The changes in cellular immune function (T cells and cell subsets [CD4+, CD8+, CD4+/CD8+], natural killer [NK] cells, C-reactive protein [CRP]) and lung function (percentage of forced expiratory volume in one second in the expected value [FEV1%], percentage of forced expiratory volume in the expected value [FEV%], percentage of forced vital capacity in the expected value [FVC%], percentage of vital capacity in the expected value in the expected value [VC%], and percentage of maximal voluntary ventilation in the expected value [MVV%]) were compared between the two groups before and after treatment. The incidence of complications and postoperative quality of life scores were compared between the two groups. Results The surgery time, indplacement time of thoracic drainage tube, postoperative hospital stay, and incision length in the observation group were shorter than those in the control group, and the intraoperative blood loss was lower than that in the control group, the differences were statistically significant (P ＜ 0.05). There was no significant difference in the number of dissected lymph nodes between the two groups (P ＞ 0.05). After treatment, the levels of CD4+, CD8+, CD4+/CD8+, NK cells, CRP, MVV%, VC%, FVC%, FEV%, and FEV1% in both groups were lower than those before treatment, and the levels of CD4+, CD8+, CD4+/CD8+, NK cells, MVV%, VC%, FVC%, FEV%, and FEV1% in the observation group were higher than those in the control group, while CRP was lower than that in the control group, the differences were statistically significant (P ＜ 0.05). The total incidence of complications and postoperative quality of life score in the observation group were lower than those in the control group, the differences were statistically significant (P ＜ 0.05). Conclusion Video assisted thoracoscopy combines with three incisions of neck in the treatment of esophageal cancer has good clinical efficacy, value of clinical further promotion.

Key words： Video assisted thoracoscopy Three incisions of neck Traditional open surgery Esophageal cancer Immune function

	Service

	E-mail this article
	Add to my bookshelf
	Add to citation manager
	E-mail Alert
	RSS
	Articles by authors
	QIAN Hairong YIN Dongming MAO Kai

Cite this article:

QIAN Hairong YIN Dongming MAO Kai. Application effect of video assisted thoracoscopy combined with three incisions of neck in patients with esophageal cancer[J]. 中国医药导报, 2022, 19(14): 105-108.

URL:

https://www.yiyaodaobao.com.cn/EN/ OR https://www.yiyaodaobao.com.cn/EN/Y2022/V19/I14/105

[1] 雷彩鹏，赵春玲，张卫国，等.胸腹腔镜辅助与传统开放三切口手术用于Ⅱ，Ⅲ期食管癌灶切除及二野淋巴结清扫的效果[J].临床医学，2019，39（5）：36-38.
[2] 王垂芳，姜峰，徐文达，等.胸腹腔镜联合根治术治疗老年食管癌患者的临床疗效及对免疫功能的影响[J].临床和实验医学杂志，2017，18（3）：277-280.
[3] 肖鑫，栾思源，杨玉赏，等.锥形管状胃联合颈部端端分层吻合在胸腹腔镜食管癌切除术中的应用价值[J].中华消化外科杂志，2019，18（6）：542-548.
[4] 卜茜，黄俊星.新辅助治疗在食管癌治疗中的应用[J].国际肿瘤学杂志，2020，47（4）：244-248.
[5] 马荣，弓磊，尚晓滨，等.腔镜食管癌根治术与开放三切口食管癌根治术的疗效分析[J].中华消化外科杂志，2018， 17（8）：804-809.
[6] 国家卫生健康委员会.食管癌诊疗规范（2018年版）[J].中华消化病与影像杂志（电子版），2019，9（4）：158-192.
[7] 陈华，丁聪，张继，等.CT影像组学对食管鳞癌病理分化程度的预测价值[J].影像研究与医学应用，2020，4（19）：7-9.
[8] 赵鸿杰，陈振岗.胸腔镜联合腹腔镜对比开胸三切口食管癌根治术治疗食管癌的临床效果[J].中国医疗器械信息，2020，26（4）：172-173.
[9] 陈海平.胸腹腔镜联合根治术与常规三切口开胸根治术治疗食管癌的近期效果[J].临床医学，2019，39（4）：83-85.
[10] 甘春娥，王若琰，刘莉.早期营养护理对食管癌根治术后患者免疫功能及营养状况的影响[J].海南医学，2020， 31（10）：1353-1356.
[11] 刘文粤，李友涛.胸腔镜腹腔镜联合食管癌根治术对食管癌患者肺功能与1年生存率的影响研究[J].吉林医学，2019，40（7）：1473-1474.
[12] 朱娟，马山蕊，李新庆，等.中国食管癌患者生活质量研究系统综述[J].中华流行病学杂志，2020，41（9）：1536-1541.
[13] 于永魁，马军，魏秀峰，等.食管癌术后早期进食显著改善患者的“疲劳/疼痛”型和“吞咽困难”症状[J].胃肠病学和肝病学杂志，2019，28（2）：179-182.
[14] 罗洞波，高云飞，吴振华，等.胸腹腔镜和三切口手术治疗食管癌的临床疗效比较[J].中国肿瘤临床与康复，2017， 26（4）：414-417.
[15] 王祥安，冯国斌，朱军，等.胸腹腔镜联合手术与传统开胸手术治疗食管癌的效果及对肺功能的影响比较[J].中国综合临床，2017，33（9）：797-801.
[16] 徐延昭，石新强，程净革，等.胸腹腔镜联合食管癌切除右颈部吻合与左颈部吻合的对比研究[J].中华胃肠外科杂志，2018，21（9）：1008-1012.
[17] 孙亚林，白玉，李廷坤，等.单腔、双腔气管插管对胸腹腔镜食管癌根治术通气效果及肺损伤的影响[J].中华医学杂志，2017，97（28）：2194-2197.
[18] 郑斌，许锦鑫，吴培训，等.密闭式单孔胸腹腔镜联合食管癌根治术的应用价值[J].中华消化外科杂志，2019， 18（3）：270-273.
[19] 丁清清，薛磊，周文颖，等.老年食管癌患者不同术式的选择和术后并发症比较[J].中华老年医学杂志，2019， 38（3）：292-295.
[20] 许挺辉.胸腹腔镜联合食管癌根治术中管状胃两种上提途径分析[J].肿瘤学杂志，2019，25（4）：376-379.
[21] 杏福宝，张雷，唐震，等.胸腹腔镜联合食管癌切除术对食管癌患者临床预后的影响[J].临床医学研究与实践，2020，5（31）：67-69.
[22] 王兴邦，蒋鹏鹏，朱思宇.管状胃经胸骨后路径与经食管床路径应用于胸腔镜联合食管癌手术对治疗成功率肺功能及术后并发症的影响[J].河北医学，2021，27（5）：757-762.
[23] 朱勇，陈晶，寇海涛，等.胸腹腔镜食管切除术手术治疗食管癌的临床效果及对患者并发症发生的影响[J].天津医科大学学报，2020，26（1）：57-61.
[24] 王庆，汪斌.颈段胸上段食管癌三切口颈部吻合术后并发症临床分析[J].现代医药卫生，2015，5（13）：1992-1994.
[25] 梁磊，王泽学.胸、腹腔镜联合手术与常规开胸手术治疗食管癌的临床效果比较[J].中国当代医药，2020，27（4）：100-102，106.