小胎龄早产儿5年前后临床状况比较分析

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Abstract Objective To compare and analyze the change of demographic characteristics, disease spectrum, clinical outcomes, and growth outcomes of preterm infants with gestational age＜32 weeks very low gestational age preterm (VLGA) in 2015 and 2020. Methods A total of 174 VLGA preterm infants hospitalized from January 1 to December 31, 2015 and 157 from January 1 to December 31, 2020 were selected from Neonatal Medical Center, Huaian Maternity and Child Healthcare Hospital Affiliated to Yangzhou University Medical College. The clinical outcome was analyzed; the demographic information, disease spectrum, and treatment of VLGA preterm infants who met discharge criteria were analyzed. Results There were statistically significant differences in the clinical outcomes of preterm infants born in different years (P < 0.05). A total of 135 VLGA preterm infants were discharged from hospital in 2015, and 125 in 2020. The gestational age and birth weight of preterm infants born in 2020 were lower than those in 2015; cesarean section rate, discharge gestational age, and discharge weight were higher than those in 2015, and hospitalization days were longer than that in 2015 (P < 0.05). The incidence of neonatal respiratory distress syndrome, septicemia, moderate and severe intraventricular hemorrhage, bronchopulmonary dysplasia, and patent ductus arteriosus in 2020 was higher than that in 2015 (P < 0.05). There was no significant difference in the growth outcomes of preterm infants born who met discharge criteria in different years (P > 0.05). Conclusion Focusing on VLGA preterm infants with lower birth mass, younger birth gestational age, and combined more critical complications results in better clinical outcomes and growth outcomes.

Key words： Very low gestational age preterm infants Disease spectrum Clinical outcomes Growth outcomes

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	LI Min1 XU Wenying2 DING Sufang2 ZHANG Li2 WANG Yumei2 PAN Zhaojun2 CAI Shizhong1

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LI Min1 XU Wenying2 DING Sufang2 ZHANG Li2 WANG Yumei2 PAN Zhaojun2 CAI Shizhong1. Comparative analysis of before and after five years of very low gestational age preterm infants[J]. 中国医药导报, 2022, 19(14): 77-80.

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https://www.yiyaodaobao.com.cn/EN/ OR https://www.yiyaodaobao.com.cn/EN/Y2022/V19/I14/77

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