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Analysis on influencing factors of cognitive dysfunction in convalescent patients with cerebral infarction |
ZHANG Chenhua1 ZHANG Chong2 ZHANG Jiafang1 LI Xiaojing1 XIAO Xia3 LYU Chenran4 WU Yiping5#br# |
1.The First Department of Neurology Medicine, Handan First Hospital, Hebei Province, Handan 056002, China;
2.Department of Function, Handan Central Hospital, Hebei Province, Handan 056000, China;
3.Department of Nursing, Handan First Hospital, Hebei Province, Handan 056002, China;
4.Medical Section, Handan First Hospital, Hebei Province, Handan 056002, China; 5.Administrative Office, Handan Central Hospital, Hebei Province, Handan 056000, China |
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Abstract Objective To analyze the influencing factors of cognitive dysfunction (CD) in convalescent patients with cerebral infarction (CI). Methods The clinical data of 100 convalescence patients with CI admitted to Handan First Hospital in Hebei Province from January 2018 to June 2019 were retrospectively analyzed, they were divided into groups according to their CD status (assessed according to Montreal cognitive assessment scale), the patient’s medical records were consulted, the patient’s relevant baseline information was recorded, and possible influencing factors were included. Logistic regression analysis was conducted to find out the influencing factors leading to the occurrence of CD in convalescent patients with cerebral infarction. Results The proportion of patients with diabetes mellitus, hyperlipidemia, and hypoalbuminemia in the occurrence group were higher than those in the non-occurrence group, and the levels of CysC and Hcy were higher than those in the non-occurrence group (P < 0.05); there was no significant difference in other relevant baseline data between the two groups (P > 0.05). Through logistic regression analysis, the results showed that the increase of the proportion of diabetes mellitus, hyperlipidemia, and hypoalbuminemia and the levels of CysC and Hcy were the influencing factors for the occurrence of CD in convalescent patients with CI (OR > 1, P < 0.05). Conclusion The occurrence of CD in convalescent patients with CI may be affected by diabetes mellitus, hyperlipidemia, hypoalbuminemia, increased CysC level, and increased Hcy level.
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[1] 李丹,刘婷,刘佳,等.急性脑梗死的认知功能障碍特点分析[J].中风与神经疾病杂志,2020,37(11):1016-1020.
[2] 孙乐山,叶荣菊,王凯.急性脑梗死患者认知功能障碍危险因素及预防策略[J].山西医药杂志,2020,49(4):420-422.
[3] 李陈芳,洪音,殷梦媚,等.急性脑梗死后认知障碍与缺血性脑卒中复发相关[J].中华老年心脑血管病杂志,2020, 22(9):947-950.
[4] 赖穗翩,陈钜涛,刘淑兰,等.缺血性脑卒中患者认知功能障碍发生的影响因素分析[J].卒中与神经疾病,2019, 26(3):334-336.
[5] 中华医学会神经病学分会,中华医学会神经病学分会脑血管病学组.中国急性缺血性脑卒中诊治指南2014[J].中华神经科杂志,2015,48(4):246-257.
[6] Naess H,Kurtz M,Thomassen L,et al. Serial NIHSS scores in patients with acute cerebral infarction [J]. Acta Neurol Scand,2016,133(6):415-420.
[7] 中国高血压基层管理指南修订委员会.中国高血压基层管理指南(2014年修订版)[J].中华健康管理学杂志,2015, 9(1):10-30.
[8] 朱朝阳.糖尿病防治指南[M].武汉:湖北科学技术出版社,2012:173.
[9] 中国成人血脂异常防治指南修订联合委员会.中国成人血脂异常防治指南(2016年修订版)[J].中国循环杂志,2016,31(10):937-950.
[10] Wong A,Law LSN,Liu W,et al. Montreal cognitive assessment [J]. Stroke,2015,642(4):342-349.
[11] Chang YL,Acosta ML,Black J. Choroidal thinning and ocular electrophysiology in a case of vascular cognitive dysfunction after stroke [J]. Clin Exp Optom,2019,102(2):184-187.
[12] 曹颖,王意君,贺清悦,等.基于老年健康综合评估探讨糖尿病与认知功能障碍的相关性研究[J].中国全科医学,2020,23(33):4252-4255.
[13] 许莉,巩忠,李慧英,等.急性脑梗死合并阻塞性睡眠呼吸暂停综合症患者认知功能障碍发生现状及相关危险因素分析[J].卒中与神经疾病,2020,27(3):327-331, 340.
[14] 邱彩霞,王庄,贺利峰,等.急性脑梗死患者血糖调节受损与早期血管性认知功能障碍的相关性研究[J].浙江医学,2020,42(1):73-75.
[15] 陈永明,吕薇,张建明,等.急性缺血性卒中患者认知功能障碍影响因素分析[J].中国卒中杂志,2017,12(9):822-826.
[16] 韩耀风,袁满琼,方亚.常见慢性病对老年人轻度认知功能障碍前期的影响[J].中国卫生统计,2019,36(2):232-235,239.
[17] 李淑恩,郑伟城,林显仙,等.脑梗死急性期低白蛋白血症与卒中后认知障碍相关性研究[J].中国神经精神疾病杂志,2020,46(2):75-79.
[18] 冯冲,吕秋石,谢怡,等.人血白蛋白对实验性蛛网膜下腔出血后认知功能的改善作用[J].中华老年心脑血管病杂志,2017,19(6):642-647.
[19] 李淑恩,郑伟城,林显仙,等.脑梗死急性期低白蛋白血症与卒中后认知障碍相关性研究[J].中国神经精神疾病杂志,2020,46(2):75-79.
[20] 李武艳,袁艳鹏.老年急性脑梗死后外周血清胱抑素C水平与认知功能障碍相关性研究[J].中国实用内科杂志,2019,39(8):705-707.
[21] 张晓愉,张昆鹏,胡岩芳,等.急性腔隙性脑梗死患者CysC、CRP、Hcy检测及其认知功能状况分析[J].解放军预防医学杂志,2019,37(9):16-18.
[22] 王竞达,谭华.急性期脑梗死患者血清胱抑素C水平与认知障碍的相关性研究[J].中华行为医学与脑科学杂志,2018,27(8):712-716.
[23] 蒯琳,洪梅.血清同型半胱氨酸,高敏C反应蛋白,胱抑素C水平与冠状动脉粥样硬化的关系[J].中国医药导报,2018,15(35):58-61.
[24] 赵建国.急性脑梗死患者血管性认知功能障碍的影响因素分析[J].河北医学,2018,24(5):841-844.
[25] 刁慧芳.老年认知障碍与同型半胱氨酸的相关性分析[J].中西医结合心脑血管病杂志,2018,16(24):3726-3728. |
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