早期肠内-肠外联合营养对颅内血肿清除术后气管切开患者的应用效果

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Abstract Objective To investigate the application effect of early enteral combined with parenteral nutrition on patients with tracheotomy after resection of intracranial hematoma. Methods Seventy-eight patients with tracheotomy incision after resection of intracranial hematoma admitted to Fuyang Second People’s Hospital from June 2018 to December 2019 were divided into parenteral group, enteral group, and combined group by random number table method, with 26 cases in each group. Enteral nutrition alone, parenteral nutrition alone, and early enteral combined and parenteral nutrition were given respectively. The nutritional status, immune level and short term prognosis were compared before and after nutrition intervention among three groups. Results The levels of total protein (TP), prealbumin (PA), albumin, transferrin (TRF) in the three groups after intervention were higher than those before intervention (P ＜ 0.05). After intervention, the levels of TP, PA, and TRF in combined group were higher than those in parenteral group, and the levels of PA and TRF in combined group were higher than those in parenteral group (P ＜ 0.05). The levels of PA and TRF in enteral group were higher than those in parenteral group (P ＜ 0.05). The levels of serum IgM, IgG, and IgA in three groups were higher than before intervention (P ＜ 0.05). After intervention, serum IgM, IgG, and IgA levels in combined group were significantly higher than those in parenteral group, and serum IgM and IgA levels in combined group were significantly higher than those in enteral group (P ＜ 0.05). The level of IgA in enteral group after intervention was higher than that in parenteral group (P ＜ 0.05). GCS scores of three groups after intervention were higher than before (P ＜ 0.05). There was no significant difference in the incidence of gastrointestinal intolerance among the three groups (P ＞ 0.05). The incidence of upper gastrointestinal bleeding in combined group was lower than that in parenteral group and enteral group (P ＜ 0.05). The total length of hospitalization in combined group was shorter than that in parenteral group and enteral group (P ＜ 0.05). Conclusions Early enteral combined with parenteral nutrition could significantly improve the immune function and nutritional status of patients with tracheotomy after resection of intracranial hematoma.

Key words： Enteral nutrition Parenteral nutrition Resection of intracranial hematoma Tracheotomy Immune function Prognosis

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	MA Juxia CHEN Li WANG Ruijie TONG Lingling▲

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MA Juxia CHEN Li WANG Ruijie TONG Lingling▲. Application effect of early enteral combined with parenteral nutrition on patients with tracheotomy after resection of intracranial hematoma#br#[J]. 中国医药导报, 2022, 19(13): 92-95.

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https://www.yiyaodaobao.com.cn/EN/ OR https://www.yiyaodaobao.com.cn/EN/Y2022/V19/I13/92

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