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| Diagnosis criteria and screening strategy of metabolic syndrome in children and adolescents |
| LI Yan1 SUN Miao2 LI Mubai2 HOU Lihui2 WANG Yingji3 |
1.Research Center of TCM Translational Medicine, the First Affiliated Hospital, Heilongjiang University of Chinese Medicine, Heilongjiang Province, Harbin 150040, China;
2.Department of Gynacology, the First Affiliated Hospital, Heilongjiang University of Chinese Medicine, Heilongjiang Province, Harbin 150040, China;
3.Teaching Office of Inorganic Chemistry and Physical Chemistry, College of Pharmacy, Harbin Medical University, Heilongjiang Province, Harbin 150081, China |
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Abstract The incidence of metabolic syndrome and obesity in children and adolescents has increased gradually. As the definition of metabolic syndrome has not been unified, the diagnosis of children and adolescents metabolic syndrome is still controversial. Although the pathogenesis is still unclear, insulin resistance and subsequent inflammation play an important role in the pathogenesis. The main clinical manifestations of metabolic syndrome are overweight and obesity, abnormal glucose metabolism, dyslipidemia, and hypertension. Fatty liver, polycystic ovary syndrome and pro-inflammatory state have close correlation with metabolic syndrome. Regular screening of metabolic syndrome should be carried out for children and adolescents with high risk factors.
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