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Research progress of refeeding syndrome in critical illnesses#br# |
WANG Qingyuan1 XIE Tuxiu2 WEI Jei1 LYU Jingjun1 |
1.Department of Emergency, Renmin Hospital of Wuhan University, Hubei Province, Wuhan 430060, China;
2.Department of General Practice, Renmin Hospital of Wuhan University, Hubei Province, Wuhan 430205, China |
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Abstract Refeeding syndrome (RFS) is a potentially life-threatening condition caused by the body’s return to eating after prolonged starvation that encompasses a range of signature laboratory abnormalities (e.g., hypophosphatemia, hypokalemia, hypomagnesemia, and Thiamine deficiency) and / or clinical symptoms. It involves intricate metabolic and nutritional transformations and is common in critical illnesses. In recent years, RFS has made some progress in critical diseases such as anorexia nervosa (AN), sepsis, and malignant tumor. To prevent and treat RFS, long-term hunger, malnutrition, low body mass index, and other related risk factors should be screened as early as possible. An initial high-calorie (30-40 kcal/[kg·d]) refeeding regimen is recommended for high-risk patients with AN, and an initial low-calorie (10-20 kcal/[kg·d]) refeeding regimen is recommended for other critically high-risk patients. This paper mainly focuses on the risk factors of RFS in critical diseases and the research progress of RFS in common critical diseases, so as to improve the attention of clinicians.
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