刘丽芳教授治疗乳腺癌上肢淋巴水肿用药规律研究

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Abstract Objective To summarize the medication rule of Professor Liu Lifang in treating upper limb lymphedema of breast cancer. Methods Clinical diagnosis and treatment prescriptions of Professor Liu in treating upper limb lymphedema of breast cancer in the First Hospital of Hunan University of Chinese Medicine from July 2018 to February 2019 were summarized and corrected, then the dispatch medication database was established. The database was deeply mined by using software. Medication frequency, medication mode and compatibility were statistically analyzed. Results A total of 71 prescriptions were included, with a total frequency of 1593 times, 58 drugs and 16 core drugs. The frequently used drugs were diuretic dampness excreting drugs, tonic drugs, blood-activating and stasis-resolving drugs and warm yang drugs. The drug meridians were mainly distributed in spleen, liver, lung, kidney, stomach and heart meridians. The drug properties were mainly warm, cold, and flat, and the drug taste was mainly sweet, bitter, and pungent. The top five drugs with the most frequent occurrence were Poria, Atractylodis Macrocephalae Rhizoma, Bupleuri Radix, Astragali Radix, and Angelicae Sinensis Radix. The most common drug combinations were Poria-Atractylodis Macrocephalae Rhizoma, Poria-Astragali Radix, and Poria-Bupleuri Radix. Six core drug combinations and three new prescriptions were obtained by cluster analysis. Conclusion Professor Liu in treating upper limb lymphedema of breast cancer is based on syndrome differentiation and treatment. The drugs used are mainly diuretic dampness excreting drugs, tonic drugs, blood-activating and stasis-resolving drugs and warm yang drugs. The treatment is based on promoting water and dampness, warming and tonifying spleen and kidney, supplemented by supplementing qi and strengthening spleen, regulating and tonifying spleen and lung, promoting blood circulation and removing blood stasis, etc., to realize the principle of “combination of disease and syndrome” in the whole process.

Key words： Upper limb lymphedema of breast cancer Association rules Liu Lifang Data mining Medication rule

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	TANG Zhong1 ZOU Wei2 LING Jie3

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TANG Zhong1 ZOU Wei2 LING Jie3. Study on medication rule of Professor Liu Lifang in treating upper limb lymphedema of breast cancer#br#[J]. 中国医药导报, 2022, 19(11): 143-146.

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https://www.yiyaodaobao.com.cn/EN/ OR https://www.yiyaodaobao.com.cn/EN/Y2022/V19/I11/143

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