慢性病患者药物相关问题评估及相关因素研究

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Abstract Objective To study the current situation of drug related problems (DRPs) in patients with chronic diseases and analyze its influencing factors. Methods The medical records of 293 patients with chronic diseases were collected from Chongqing Dianjiang People’s Hospital from October 2020 to February 2021, and the incidence of DRPs was analyzed. According to the occurrence of DRPs, patients were divided into the occurrence group (132 cases) and the non-occurrence group (161 cases). The clinical data of the two groups were compared, and the influencing factors of the occurrence of DRPs in patients with chronic diseases were analyzed by binary logistic regression model. Results In this study, the incidence of DRPs was 45.05%, and a total of 165 DRPs were found. Bayliff evaluation results showed that DRPs caused six grade zero hazards, 133 grade one hazards, and 26 grade two hazards. There were statistically significant differences in age, number of complications, types of medication, and medication compliance between the two groups (P ＜ 0.05). Multivariate analysis showed that age 60-75 years old, variety types of medication, number of complications, and poor medication compliance were independent risk factors for DRPs in patients with chronic diseases (OR ＞ 1, P ＜ 0.05). Conclusion Patients with chronic diseases have a high incidence of DRPs, and patients’ age, number of complications, medication varieties, and medication compliance all affect the risk of DRPs.

Key words： Chronic diseases Drug-related problems Influence factors Rational drug use

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	PENG Yang ZHU Bimin HE Lin ZHANG Lu LIN Yihong

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PENG Yang ZHU Bimin HE Lin ZHANG Lu LIN Yihong. Evaluation of drug-related problems and related factors in patients with chronic diseases#br#[J]. 中国医药导报, 2022, 19(11): 61-63,80.

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https://www.yiyaodaobao.com.cn/EN/ OR https://www.yiyaodaobao.com.cn/EN/Y2022/V19/I11/61

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