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Research on the medication rule of Professor Xie Zuogang in the treatment of chronic prostatitis based on data mining#br# |
FANG Yuekun XIE Zuogang |
Department of Andrology, Wenzhou Hospital of Integrated Traditional Chinese and Western Medicine, Zhejiang Province, Wenzhou 325700, China |
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Abstract Objective To study the medication rule of Professor Xie Zuogang in the treatment of chronic prostatitis. Methods The medical records of Professor Xie Zuogang in the andrology clinic of Wenzhou Hospital of Integrated Traditional Chinese and Western Medicine, Zhejiang Province from January 2019 to August 2020 were selected, the relevant database was established, and the relevant core drug combinations and drug compatibility laws hidden in the prescription were mined by frequency analysis, association rule analysis, and entropy cluster analysis. Results A total of 356 cases and 1015 prescriptions were included in this study, involving 267 kinds of drugs. The four Qi of medicine were mainly cold and warm, and the five flavours were mainly bitter and pungent. The commonly used channel tropism was mainly liver meridian. There were 23 drugs used more than 220 times, and the top five were Poria, Ramulus Cinnamomi, Radix Glycyrrhizae, Radix Scutellariae, and Radix Bupleuri. Core prescriptions were mined through association rule analysis. Based on entropy cluster analysis of complex system, 12 core combinations of traditional Chinese medicine and six new prescriptions were evolved. Conclusion Professor Xie Zuogang’s treatment of prostatitis with traditional Chinese medicine mainly focuses on “soothing liver and regulating qi”, “ activating blood and removing stasis”, “clearing heat and promoting diuresis”, and “tonifying kidney and benefiting qi”.
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