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Analysis on medication rule of compound Chinese medicine in the external treatment of uremic pruritus#br# |
ZHAO Li JIN Qiying QU Jianhua |
Department of Dermatology, Beijing Hospital of Traditional Chinese Medicine, Capital Medical University, Beijing 100010, China |
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Abstract Objective To explore the medication rule of Chinese medicine in the external treatment of uremic pruritus based on data mining. Methods The literatures on Chinese medicine in the external treatment of uremic pruritus published in PubMed, CNKI, VIP Chinese periodical service platform, Wanfang data knowledge service platform, China biomedical literature service system and other databases from the establishment of the database to December 2020 were collected and sort outed. The frequency of Chinese medicine, drug properties, drug taste and menstruation were counted. Association rule analysis and cluster analysis were carried out for high-frequency drugs. Results A total of 77 prescriptions of Chinese medicine and 105 drugs were included in the study. The most frequently used drug was Kochiae Fructus. The highest support of association rules was Chuanxiong Rhizoma→Angelicae Sinensis Radix. Five cluster prescriptions were obtained. Conclusion The core of Chinese medicine in the external treatment of uremic pruritus is nourishing yin and tonifying blood. Pay attention to clearing heat and draining dampness, promoting blood circulation and removing blood stasis, and give consideration to detoxification.
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