墨莲祛白汤联合他克莫司软膏治疗肾虚血瘀型稳定期白癜风的临床效果

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Abstract Objective To investigate the clinical effect of Molian Qubai Decoction combined with Taclimus Ointment in the treatment of vitiligo at stable stage of kidney deficiency and blood stasis type. Methods A total of 56 patients with vitiligo at stable stage of kidney deficiency and blood stasis type admitted to Department of Dermatology, Cangzhou Hospital of Integrated Traditional Chinese Medicine and Western Medicine of Hebei Province from September 2020 to June 2021 were selected and they were divided into treatment group and control group according to random number table method, with 28 patients in each group. The treatment group was treated with Molian Qubai Decoction combined with Taclimus Ointment, and the control group was treated with Taclimus Ointment. The two groups were routinely given Compound Glycyrrhizin Tablets, and the two groups were treated for three consecutive courses. The results of treatment and dermatology life quality index (DLQI) were compared between the two groups, and the levels of tumor necrosis factor-α (TNF-α) in peripheral blood of the two groups were compared. Results The clinical effect of treatment group was better than that of control group, the difference was statistically significant (P ＜ 0.05). After treatment, the DLQI and TNF-α level in two groups were decreased compared with before treatment, and those in treatment group were lower than those in control group, the differences were statistically significant (P ＜ 0.05). Conclusion Molian Qubai Decoction combined with Taclimus Ointment can improve the quality of life of patients with vitiligo in stable stage of kidney deficiency and blood stasis type, reduce the inflammatory state and improve the curative effect.

Key words： Molian Qubai Decoction Tacrolimus Ointment Vitiligo Clinical curative effect

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	DU Kaiqing1 GUO Wen1 GONG Ke1 GUO Jianhui2 SHEN Yana3

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DU Kaiqing1 GUO Wen1 GONG Ke1 GUO Jianhui2 SHEN Yana3. Clinical effect of Molian Qubai Decoction combined with Tachlimus Ointment in the treatment of vitiligo at stable stage of kidney deficiency and blood stasis type#br#[J]. 中国医药导报, 2022, 19(10): 103-106.

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https://www.yiyaodaobao.com.cn/EN/ OR https://www.yiyaodaobao.com.cn/EN/Y2022/V19/I10/103

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