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A case report of SOX regimen combined with terriprizumab in treatment of intermediate and advanced combined hepatocellular-cholangiocarcinoma#br# |
HE Yalin1 YANG Jiaxin1 CHENG Zhiqiang2 |
1.Graduate School, Beijing University of Chinese Medicine, Beijing 100029, China;
2.Department of Internal Oncology Integrated Chinese and Western Medicine, China-Japan Friendship Hospital, Beijing 100029, China |
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Abstract Combined hepatocellular-cholangiocarcinoma (cHCC-CCA) is a rare type of primary hepatocellular carcinoma, which has differentiation characteristics of hepatocellular carcinoma and cholangiocarcinoma, it is considered an aggressive tumor with poor prognosis and little improvement in survival. For unresectable cHCC-CCA, the evidence of standard treatment is limited, and there are few reports about it at home and abroad. This paper reports a case of stage ⅢB cHCC-CCA who was unable to undergo radical resection at the time of diagnosis, after 15 cycles of SOX chemotherapy plus terriprizumab, finally, the diagnosis and treatment process of complete pathological remission was achieved. In order to improve the clinical diagnosis and treatment level of cHCC-CCA, retrospective case analysis and literature review.
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