温针灸联合仿生物电刺激治疗肾虚血瘀型卵巢储备功能减退患者的临床效果

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Abstract Objective To observe the clinical effect of warming acupuncture combined with imitating bioelectric stimulation in the treatment with diminished ovarian reserve (DOR) patients of kidney deficiency and blood stasis syndrome. Methods A total of 60 patients with DOR from Huangshi Maternal and Child Health Care Hospital, Hubei Province from January to June 2021, they were divided into combination group and western medicine group, according to the random number table method, with 30 cases in each group. The combination group was treated with warming acupuncture combined with imitating bioelectric stimulation, and western medicine group was treated with Estradiol Valerate Tablet/Cycloproterone Estradiol Tablets, both groups were treated for three courses. The curative effect of traditional Chinese medicine syndrome was compared, traditional Chinese medicine clinical syndrome scores, follicle stimulating hormone (FSH), FSH/luteinizing hormone (LH), peak systolic velocity (PSV), resistance index (RI), pulse index (PI), ovarian volume (OV), anti-mullerian hormone (AMH), and antral follicle count (AFC) before and after treatment were compared. Results The curative effect of traditional Chinese medicine syndrome in combined group was better than that in western medicine group, and the difference was statistically significant (P < 0.05). Before treatment, there were no significant differences in traditional Chinese medicine syndrome scores between two groups (P > 0.05); after treatment, the traditional Chinese medicine syndrome scores of two groups were lower than those before treatment, and combined group was lower than western medicine group, and the differences were statistically significant (P < 0.05). Before treatment, there were no significant differences in FSH, FSH/LH, AMH, AFC, OV, PSV, RI, and PI between two groups (P > 0.05). After treatment, AMH in combination group was higher than that before treatment, and combination group was higher than western medicine group, and the differences were statistically significant (P < 0.05); after treatment, AFC and OV in two groups were higher than those before treatment, and the differences were statistically significant (P < 0.05); but there were no statistical significance in AFC and OV between two groups (P > 0.05); after treatment, PSV in both groups were higher than those before treatment, and combination group was higher than western medicine group, and the differences were statistically significant (P < 0.05); after treatment, FSH, FSH/LH, RI, and PI in two groups were lower than those before treatment, and the differences were statistically significant (P < 0.05); but there were no statistical significance in FSH, FSH/LH, RI, and PI in two groups (P > 0.05). Conclusion Warming acupuncture combined with imitating bioelectric stimulation can effectively relieve the clinical symptoms of DOR patients with kidney deficiency and blood stasis syndrome, increase ovarian blood perfusion, increase the ovarian volume, regulate sex hormone levels, improve AMH and AFC, and then improve the ovarian reserve capacity.

Key words： Warming acupuncture Imitating bioelectric stimulation Diminished ovarian reserve Kidney deficiency and blood stasis syndrome

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	HU Jing1 YUAN Yuning2 CHENG Si1

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HU Jing1 YUAN Yuning2 CHENG Si1. Clinical effect of warming acupuncture combined with imitating bioelectric stimulation in the treatment with diminished ovarian reserve patients of kidney deficiency and blood stasis syndrome #br#[J]. 中国医药导报, 2022, 19(8): 72-76.

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https://www.yiyaodaobao.com.cn/EN/ OR https://www.yiyaodaobao.com.cn/EN/Y2022/V19/I8/72

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