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| Comparison of the emergency curative effect and the changes of plasma B-type natriuretic peptide and procalcitonin levels between lung cancer and pneumonia with pleural effusion patients |
| LI Xiao1 XU Jing2 |
1.Department of Pneumology, the People′s Hospital of Gaoxin District in Chongqing City, Chongqing 400039, China;
2.Department of Respiratory and Critical Care Medicine, the Second Hospital Affiliated to Army Medical University, Chongqing 400037, China |
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Abstract Objective To compare the emergency curative effect and the changes of plasma B-type natriuretic peptide (BNP) and procalcitonin (PCT) levels between lung cancer and pneumonia with pleural effusion patients. Methods A total of 52 patients with lung cancer with pleural effusion admitted to the People′s Hospital of Gaoxin District in Chongqing City from May 2015 to May 2017 were selected as lung cancer group; and 52 patients with pneumonia with pleural effusion were selected as pneumonia group during the same period. Two groups of patients were treated with strengthening the heart, diuresis, anti-inflammatory, anti-infection and limiting fluid intake therapies. The chest CT scan was conducted before the treatment and 7 days after treatment. The therapeutic effect of pneumonitis, pleural effusion and plasma PCT and BNP levels before and after treatment were observed between the two groups. Results The total effective rate of pneumonia treatment in the pneumonia group and the lung cancer group was 96.15% and 82.69%， respectively（P ＞ 0.05）. The total effective rate of pleural effusion in the pneumonia group and the lung cancer group was 84.62% and 44.23%, respectively（P ＜ 0.05）. The plasma BNP and PCT levels of patients in pneumonia group after treatment were significantly lower than those before treatment, while the plasma PCT level in lung cancer group after treatment was significantly lower than that before treatment (P ＜ 0.05). Conclusion In contrast to the patients with lung cancer with pleural effusion, the clinical conventional treatments, such as strengthening the heart, diuresis, anti-inflammatory, anti-infection and limiting fluid intake, are more suitable in the treatment for patients with pneumonia with pleural effusion, which can effectively improve heart function and relieve inflammatory response.
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