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| Research progress in opioid addiction related conditions#br# |
| LIU Peng LI Ping DU Hongxia WEI Ming |
| Department of Pharmacology and Toxicology, Institute of Basic Medicine Science, Xi’an Medical University, Shaanxi Province, Xi’an 710021, China |
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Abstract Drug addiction is a kind of recurrent and chronic brain disease, and the recognition of the biological mechanism of drug addiction has become an urgent requirement to develop targeted and effective treatment methods. One of the major limitations of opioids is that opioids are inevitably addictive in their application. This article provides an overview of opioid addiction and summarizes the new findings of existing researches from five aspects: opioid classification, opioid receptors，current status and treatment of drug abuse, genetic susceptibility to addiction, important brain regions and neural circuits related to Morphine addiction, in order to help researchers to form a preliminary, overall understanding of opioid addiction.
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