微波凝固辅助强脉冲光治疗玫瑰痤疮的效果

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Abstract Objective To evaluate the efficacy and safety of microwave coagulation assisted intense pulse light (IPL) in the treatment of rosacea. Methods From February 2014 to January 2017, 64 patients with rosacea in the Department of Dermatology in Lishilu Outpatient, General Hospital of the PLA Rocket Force were divided into observation group and control group according to random number table method, with 32 cases in each group. The observation group was treated with IPL and microwave to coagulate the dilated capillaries, while the control group was treated with IPL only. The clinical effects, side effects, symptom scores and dermatology life quality index (DLQI) scores before and after treatment in the two groups were observed and compared. Results The total effective rate of the observation group was significantly higher than that of the control group at 3, 6, 9 weeks after treatment (P ＜ 0.05), but there was no significant difference between the two groups at 12 weeks after treatment (P ＞ 0.05). The overall difference of effects between groups, time effects and interaction effects of total score of skin lesions and DLQI score was statistically significant in the two groups (P ＜ 0.05). Further comparison showed that the total score of skin lesions and DLQI score at each time point after treatment were significantly lower than those in the same group before treatment (P ＜ 0.05). The total score of skin lesions at 3, 6, 9, 12 weeks after treatment, and DLQI score at 3, 6, 9 weeks after treatment in the observation group were decreased more significantly than those of control group (P ＜ 0.05), however, there was no significant difference at 12 weeks after treatment in DLQI score between the two groups (P > 0.05). Conclusion Microwave coagulation assisted IPL in the treatment of rosacea patients with telangiectasia on the nasal and surrounding is effective, safe and reliable, the recovery time of the patients is short, the quality of life is obviously improved, which is worth popularizing in clinic.

Key words： Intense pulsed light Microwave Rosacea Clinical effect

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	WANG Huaixiang LI Jianming▲

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WANG Huaixiang LI Jianming▲. Effect of microwave coagulation assisted intense pulsed light in the treatment of rosacea[J]. 中国医药导报, 2018, 15(26): 113-116.

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http://www.yiyaodaobao.com.cn/EN/ OR http://www.yiyaodaobao.com.cn/EN/Y2018/V15/I26/113

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