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| Changes and clinical significance of serum PCT, CRP, and IL-6 levels in patients with coronary heart disease complicated with pulmonary infection in department of cardiology#br# |
| ZHAN Yongzhong1 CHENG Longfei2 LIN Xucheng1 |
1.Department of Cardiology, Chaozhou Central Hospital, Guangdong Province, Chaozhou 521000, China;
2.Department of laboratory, Chaozhou Central Hospital, Guangdong Province, Chaozhou 521000, China |
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Abstract Objective To investigate the changes and clinical significance of serum procalcitonin (PCT), C-reactive protein (CRP), and interlukin-6 (IL-6) levels in patients with coronary heart disease complicated with pulmonary infection in department of cardiology. Methods The diagnosis and treatment situation of 80 patients with coronary heart disease who were treated in Chaozhou Central Hospital in Guangdong Province (“our hospital” for short) from March 2018 to March 2021 were retrospectively analyzed. According to the diagnostic criteria of pulmonary infection, they were divided into infection group (32 cases) and non-infection group (48 cases), and 50 healthy people who underwent physical examination in our hospital during the same period were selected as control group. Serum levels of PCT, CRP, and IL-6 in each group were detected and compared, and the degree of coronary lesions in the infection group was evaluated according to Gensini score. Pearson linear correlation was used to analyze the correlation between PCT, CRP, IL-6 levels, and Gensini score. Results The serum levels of PCT, CRP, and IL-6 in the infection group and non-infection group were significantly higher than those in the control group, while the serum PCT, CRP, and IL-6 levels in the infection group were higher than those in the non-infection group, and the differences were statistically significant (P ＜ 0.05). There was a statistically significant difference in Gensini score between the two groups (P ＜ 0.01). Pearson linear correlation analysis showed that the levels of serum PCT (r = 0.603), CRP (r = 0.685), IL-6 (r = 0.574) in the infection group were positively correlated with Gensini scores (P ＜ 0.01). Conclusion The serum levels of PCT, CRP, and IL-6 in patients with coronary heart disease complicated with pulmonary infection in the department of cardiology are significantly increased. The detection of the above indicators has certain diagnostic value for coronary heart disease complicated with pulmonary infection.
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