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| Association between triacyl-glucose index and hyperuricemia in males in our hospital#br# |
| Mayina Kahaer ZHANG Bei LIANG Meiting CHEN Wujin TIAN Tingting SUN Yuping |
| Department of Microbiology, College of Basic Medicine in Xinjiang Medical University, Xinjiang Uygur Autonomous Region, Urumqi 800017, China |
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Abstract Objective To investigate the relationship between triacylglycerol glucose (TyG) index and hyperuricemia in men. Methods A total of 821 male physical examination population from the First Affiliated Hospital of Xinjiang Medical University from September 2018 to June 2020 were selected as the research subjects for questionnaire survey, physical examination and detection of serum biochemical indicators. According to whether they had hyperuricemia or not, they were divided into hyperuricemia group (314 cases) and control group (507 cases). Results The education level and income level of the hyperuricemia group were lower than those of the control group (P ＜ 0.05); the body weight, waist-hip ratio, body mass index, fasting blood glucose, uric acid, and TyG index of the hyperuricemia group were higher than those of the control group (P ＜ 0.05). According to the quartile analysis of TyG index, with the increase of TyG index, the level of uric acid increased. After adjusting for various confounding factors, the serum uric acid level increased by 21.683 μmol/L for each standard deviation increase of TyG. Compared with the lowest quartile of the adjusted model, serum urate concentrations in the highest quartile increased by 35.804 μmol/L (P ＜ 0.05). Multivariate logistic regression showed that the risk of hyperuricemia increased by 68.9% for each standard deviation increase in the TyG index after adjusting for multiple confounders. The risk in the highest quartile was 0.592 times that in the lowest quartile (P ＜ 0.05). Conclusion Male TyG index has a significant correlation with hyperuricemia, and it has certain validity in assessing the risk of hyperuricemia.
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