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| Clinical effect of the acupoints combination of kidney-benefiting and marrow-filling of electroacupuncture in the treatment of Alzheimer’s disease with syndrome of marrow sea insufficiency#br# |
| LIU Yong1 YU Haoheng2 |
1.The First Department of Acupuncture and Moxibustion, the First Affiliated Hospital of Heilongjiang University of Chinese Medicine, Heilongjiang Province, Harbin 150040, China;
2.Graduate School, Heilongjiang University of Chinese Medicine, Heilongjiang Province, Harbin 150040, China |
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Abstract Objective To explore the clinical effect of the acupoints combination of kidney-benefiting and marrow-filling of electroacupuncture in the treatment of Alzheimer’s disease with syndrome of marrow sea insufficiency. Methods A total of 60 patients recruited from the outpatient and inpatient department of the First Affiliated Hospital of Heilongjiang University of Chinese medicine from September 2019 to November 2020 were selected, according to random number table method, they were divided into acupuncture group (30 cases) and electroacupuncture point group (30 cases). The acupuncture group was treated with traditional acupuncture and moxibustion, and the electroacupuncture point group was treated with acupoints combination of kidney-benefiting and marrow-filling. Both groups were treated for four weeks. The mini mental state examination (MMSE), classification of dementia syndrome in traditional Chinese medicine (SDSD), and Montreal cognitive assessment (MoCA) was compared between the two groups before and after treatment, and the efficacy index was calculated as the efficacy evaluation. Results After treatment, the MMSE and MOCA scores of the two groups were higher than those before treatment (P ＜ 0.05), and the electroacupuncture point group was higher than that of the acupuncture group (P ＜ 0.05); the SDSD scores of the two groups were lower than those before treatment (P ＜ 0.05), and the electroacupuncture point group was lower than that of the acupuncture group (P ＜ 0.05). The therapeutic indexes of MMSE, SDSD and MOCA in electroacupuncture point group were higher than those of the acupuncture group (P ＜ 0.05). Conclusion Both traditional acupuncture and acupoints combination of kidney-benefiting and marrow-filling have definite curative effects on Alzheimer’s disease with syndrome of marrow sea insufficiency, and acupoints combination of kidney-benefiting and marrow-filling is better than traditional acupuncture in the treatment of Alzheimer’s disease with syndrome of marrow sea insufficiency.
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