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| Inspection of changes in cerebral hemodynamics after carotid artery stenting at different ages |
| DAI Mingming1 SU Qingjie1 YU Hang2 LONG Faqing1 WU Yingman1 WANG Desheng1 WANG Bufei1 GAO Chang3 |
1.Department of Neurology, the Second Affiliated Hospital of Hainan Medical University, Hainan Province, Haikou 570311, China;
2.Department of Critical Care Medicine, the Second Affiliated Hospital of Hainan Medical University, Hainan Province, Haikou 570311, China;
3.Department of Pathophysiology, Hainan Medical University, Hainan Province, Haikou 570311, China |
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Abstract Objective To compare the changes in cerebral hemodynamics after carotid artery stenting (CAS) at different ages. Methods A retrospective analysis of clinical date of 50 patients who had been received carotid artery stenting in the Department of Neurology of the Second Affiliated Hospital of Hainan Medical University from June 2015 to June 2017. The patients were divided into three groups according to the age: middle age-group(< 60 years old, n = 20), older age-group (60-＜ 80 years old, n = 68), and advanced age-group (≥ 80 years old, n = 12). Color Doppler imaging (CDFI) combined with transcranial Doppler ultrasound (TCD) was used to measure the local diameter of the narrow place of posterior carotid artery (D), the peak systolic velocity (PSV) of the narrow place, vascular resistance index (RI), the systolic peak velocity of the middle cerebral artery (PSV) in the affected side, the vascular pulsation index (PI) and cerebrovascular reactivity (CVR) before and 1 week after CAS, and then all these data were compared before and after operation at different ages. Results After the carotid artery stenting, the diameter of the original stenosis was significantly increased, and the levels of PSV and RI were significantly decreased (P < 0.05). The PSV and PI of the MCA in the affected side were higher than those before operation, and CVR was significantly improved (P < 0.05). Among the three groups, there was the most significant improvement of cerebral hemodynamics in middle age-group(P < 0.05). However, the changes in cerebral hemodynamics in older age-group was not significantly improved when compared with advanced age-group（P ＞ 0.05）. Conclusion CAS is an effective treatment in carotid artery stenosis in all the patients. Furthermore, the patients whose age < 60 years old have the most significant improvement in cerebral hemodynamics.
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