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| Research progress on prevention and treatment of Alzheimer’s disease with traditional Chinese medicine based on gut microbiota#br# |
| WANG Yang1 ZHAO Jian2 WANG Di2 YANG Bo3 ZHENG Shijia4 ZHOU Zhongguang1 |
1.College of Basic Medicine, Heilongjiang University of Chinese Medicine, Heilongjiang Province, Harbin 150040, China;
2.Department of Acupuncture, the Second Affiliated Hospital of Heilongjiang University of Chinese Medicine, Heilongjiang Province, Harbin 150040, China; 3.College of Pharmacy, Heilongjiang University of Chinese Medicine, Heilongjiang Province, Harbin 150040, China;
4.Tianwenshan Agricultural Development Company, Heilongjiang Province, Harbin 150040, China |
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Abstract Intestinal microecology is a hotspot of research on life science in recent years. Gut microbiota and its metabolites regulate host’s behavior and cognitive function, and are closely related to the occurrence and development of Alzheimer’s disease (AD), gut microbiota has become a new target for the prevention and treatment of AD. Traditional Chinese medicine has advantages in regulating gut microbiota, and it is widely used in the prevention and treatment of AD. Targeting gut microbiota through traditional Chinese medicine has become a key breakthrough in anti-AD treatment. This paper describes the relationship between gut microbiota and AD, and summarizes the current situation of the research on the control of gut microbiota by traditional Chinese medicine, in order to provide research directions and ideas for strengthening the understanding of AD and the development of anti-AD drugs.
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