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Clinical analysis of uterine artery embolization combined with Ethacridine and Mifepristone for induction of mid-term pregnancy in placental predisposition #br# |
YANG Xiaorong1 JIN Xuan1 DING Juan1 LI Junqiang2▲ |
1.Department of Obstetrics, Sichuan Jinxin Women & Children’s Hospital, Sichuan Province, Chengdu 610011, China;
2.Department of Obstetrics and Gynecology, the Third People’s Hospital of Chengdu, Sichuan Province, Chengdu 610031, China |
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Abstract Objective To investigate the application effect of uterine artery embolization combined with Ethacridine and Mifepristone for induction of mid-term pregnancy in placental predisposition. Methods From January 2018 to September 2020, 97 cases with placental predisposition admitted to Department of Gynecology and Obstetrics, Sichuan Jinxin Women & Children’s Hospital were selected. Uterine artery embolization was performed after admission for all patients, they were divided into experimental group (51 cases) and control group (46 cases) according to random number table method after embolization. Experimental group received Mifepristone oral administration combined with Ethacridine amniotic cavity injection for labor induction; and control group received Ethacridine amniotic cavity injection to induce labor. The effect of induced labor, time from intervention to delivery, the amount of blood loss, residual placenta membrane, length of stay, and total hospitalization cost were compared between two groups. Results All 97 patients were successfully induced labor without using other methods. The time from intervention to delivery in experimental group was shorter than that in control group, and the amount of blood loss, and residual placenta membrane rate were lower than those in control group, with statistical significances (P < 0.05). There were no significant differences in length of stay and total hospitalization cost between two groups (P > 0.05). Conclusion For the patients with placental predisposition in mid-term pregnancy and no history of cesarean section or placental implantation, the labor induction with Ethacridine combined with Mifepristone after uterine artery embolization is satisfactory, safe and reliable, and worthy of clinical reference.
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