斑马鱼肿瘤模型的研究进展

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Abstract Zebrafish have been successfully widely used as a research models for human-related diseases in the past decade due to their unique advantages in small-scale Organisms such as in vitro fertilization, embryo transparency and strong reproductive ability. At present, the gene manipulation technology for zebrafish has been quite mature, Targeting to induce or knock out certain genes in the body and change its expression level, it is easy to replicate some human tumor diseases on zebrafish, so various types of zebrafish tumor models can be established, and are suitable for conducfing reserch on related mechanisms. This article reviews the advantages of zebrafish as a tumor model and the research of various types of zebrafish tumor models, and the application value of zebrafish as a model animal in the study of anti-tumor drugs was analyzed.

Key words： Zebrafish Tumor model Drug research Application value

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	LI Cuixia SU Xiulan

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LI Cuixia SU Xiulan. Progress in research on zebrafish tumor model[J]. 中国医药导报, 2018, 15(26): 22-25.

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http://www.yiyaodaobao.com.cn/EN/ OR http://www.yiyaodaobao.com.cn/EN/Y2018/V15/I26/22

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