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Research progress on the related structure and function of astrocytes in migraine#br# |
LI Zhijuan LIU Lu LI Bin |
Department of Acupuncture and Moxibustion, Beijing Hospital of Traditional Chinese Medicine, Capital Medical University Beijing Key Laboratory of Acupuncture Neuromodulation, Beijing 100010, China |
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Abstract Migraine is a common disability disease in clinic, and its pathogenesis is complicated. Pain hypersensitivity is a reaction of central sensitization. With the deepening of research, glial cells play an important role in the occurrence and development of pain, and astrocytes have a strong activation response in the development and persistence of pain. Astrocytes participate in the occurrence and development of migraine through gap junctions, intersynaptic glutamate, transporters, and inhibition of cortical spreading. This article summarizes the relationship between the structure and function of astrocytes and migraine, and provides a new direction for the research and treatment of migraine.
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