负压伤口疗法在肥胖产妇中应用效果的meta分析

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Abstract Objective To investigate the effect of negative pressure wound therapy (NPWT) in maternal obesity, and providing the best evidence to clinical practice. Methods PubMed, EMBase, the Cochrane Central Register of Controlled Trials, ClinicalTrial.gov, CNKI, and WanFang data were systematically searched from create database to December, 2020 to identify relevant randomized controlled trials. Two authors independently read and extracted data from the selected studies. Review Manager 5.3 was applied to analyze the collected data; TSA 0.9 was used to evaluate the reliability of the study results. Results A total of nine articles were included. Meta analysis results showed that, there was no significant difference in surgical site infection rate between two groups (RR = 0.85, 95%CI: 0.66-1.08, P = 0.18); the incidence of site complications including site infection in NPWT group was lower than that in conventional dressing group (RR = 0.81, 95%CI: 0.68-0.97, P = 0.02); the incidence of site complications except site infection in NPWT group was lower than that in conventional dressing group (RR = 0.75, 95%CI: 0.66-0.86, P < 0.0001); there was no statistically significant difference in the readmission rate between two groups (RR = 1.19, 95%CI: 0.62-2.27, P = 0.60). Conclusion NPWT can effectively reduce postoperative site complication rate in maternal obesity, but it cannot reduce surgical site infection rate and readmission rate.

Key words： Cesarean section Obese Negative pressure wound therapy Meta-analysis

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	HE Huilin1 HE Fang1 HUANG Huaping2▲

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HE Huilin1 HE Fang1 HUANG Huaping2▲. Meta analysis of negative pressure wound therapy in maternal obesity#br#[J]. 中国医药导报, 2021, 18(36): 85-90.

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https://www.yiyaodaobao.com.cn/EN/ OR https://www.yiyaodaobao.com.cn/EN/Y2021/V18/I36/85

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