艾滋病免疫重建不全中西医治疗研究进展

Abstract
Figure/Table
References (29)
Related Citation (15)

Download: PDF (592 KB) HTML (1 KB)
Export: BibTeX | EndNote (RIS)

Abstract Acquired immune deficiency syndrome (AIDS) is a major public health problem worldwide. Some patients have a series of complications due to incomplete immune reconstitution, which accelerates the disease process and seriously affects their quality of life. In recent years, domestic and foreign scholars have carried out a large number of studies in the field of incomplete immune reconstitution of AIDS. This paper reviews AIDS incomplete immune reconstitution pathogenesis and treatment progress from modern medical and traditional medical perspectives by reviewing relevant studies in recent years. It is found that Western medicine focuses on the decline of the number of CD4+T lymphocytes and adopts individualized treatment for different causes, while traditional Chinese medicine concentrates on the vital qi exhaustion of five zang viscera and chooses different strengthening programs. Both Western medicine and traditional Chinese medicine have unique advantages. However, the combination of traditional Chinese and Western medicine has more advantages in effect and safety, but lacks more powerful evidence-based medical evidence, which is worth further digging, in order to form a complete and standardized treatment system.

Key words： Acquired immune deficiency syndrome Incomplete immune reconstruction Integrated traditional Chinese and Western medicine CD4+T lymphocytes Immune activation

	Service

	E-mail this article
	Add to my bookshelf
	Add to citation manager
	E-mail Alert
	RSS
	Articles by authors
	KE Jingwen1 XIAO Mingzhong2 LIN Lianmei1 LIU Jianzhong2

Cite this article:

KE Jingwen1 XIAO Mingzhong2 LIN Lianmei1 LIU Jianzhong2. Research progress of traditional Chinese and Western medicine on acquired immune deficiency syndrome incomplete immune reconstitution#br#[J]. 中国医药导报, 2021, 18(36): 50-53.

URL:

https://www.yiyaodaobao.com.cn/EN/ OR https://www.yiyaodaobao.com.cn/EN/Y2021/V18/I36/50

[1] 中华中医药学会防治艾滋病分会.艾滋病免疫功能重建不良中西医协同治疗专家共识[J].中医学报，2020，35（2）：281-284.
[2] Yang X，Su B，Zhang X，et al. Incomplete immune reconstitution in HIV/AIDS patients on antiretroviral therapy：Challenges of immunological non-responders [J]. J Leukoc Biol，2020，107（4）：597-612.
[3] Ferrando-Martinez S，De Pablo-Bernal RS，De Luna-Romero M，et al. Thymic Function Failure Is Associated With Human Immunodeficiency Virus Disease Progression [J]. Clin Infect Dis，2017，64（9）：1191-1197.
[4] Marziali M，De Santis W，Carello R，et al. T-cell homeostasis alteration in HIV-1 infected subjects with low CD4 T-cell count despite undetectable virus load during HAART [J]. AIDS，2006，20（16）：2033-2041.
[5] Sturm R，Xanthopoulos L，Heftrig D，et al. Regulatory T Cells Modulate CD4 Proliferation after Severe Trauma via IL-10 [J]. J Clin Med，2020，9（4）：1052.
[6] Sokoya T，Steel HC，Nieuwoudt M，et al. HIV as a Cause of Immune Activation and Immunosenescence [J]. Mediators Inflamm，2017，2017：1-16.
[7] Ramendra R，Isnard S，Lin J，et al. Cytomegalovirus Seropositivity Is Associated With Increased Microbial Translocation in People Living With Human Immunodeficiency Virus and Uninfected Controls [J]. Clin Infect Dis，2020， 71（6）：1438-1446.
[8] Doitsh G，Galloway NL，Geng X，et al. Cell death by pyroptosis drives CD4 T-cell depletion in HIV-1 infection [J]. Nature，2014，505（7484）：509-514.
[9] 田云飞，肖江，韩宁，等.HIV/AIDS患者免疫重建不良的研究进展[J].中华实验和临床感染病杂志：电子版，2015， 9（4）：462-467.
[10] 李玉枝，赵稳，平岖，等.外源性IL-15/IL-10受体阻断剂对HIV-1感染者T细胞体外增殖的影响[J].热带医学杂志，2016，16（3）：275-280，292.
[11] Zhang Z，Fu J，Xu X，et al. Safety and immunological responses to human mesenchymal stem cell therapy in difficult-to-treat HIV-1-infected patients [J]. AIDS，2013，27（8）：1283-1293.
[12] Jim?伢nez-Sousa M?譧，Martínez I，Medrano LM，et al. Vitamin D in Human Immunodeficiency Virus Infection：Influence on Immunity and Disease [J]. Front Immunol，2018，9：458.
[13] Bandera A，Colella E，Rizzardini G，et al. Strategies to limit immune-activation in HIV patients [J]. Expert Rev Anti Infect Ther，2016，15（1）：43-54.
[14] 李婉，赵海潞.浅论中医正气理论与现代免疫学的内在联系[C]//第十二届全国免疫学学术大会摘要汇编.中国免疫学会，2017：425.
[15] 姜素丽，李亚，田燕歌，等.调补肺肾三法对COPD大鼠T淋巴细胞亚群及CD4+CD25+的影响及远后效应[J].中国中西医结合杂志，2013，33（11）：1538-1544.
[16] 许剑，陈耀凯.从中医“脾系”与“免疫”的相关性探讨艾滋病论治[J].中国艾滋病性病，2020，26（10）：1129-1131.
[17] 杨巧丽，郑好飞，刘颖.温肾法与艾滋病中晚期患者的免疫重建[J].中医杂志，2016，57（18）：1614-1615.
[18] 李育萍，许琪华，陈思言，等.92例灵芝联合高效抗反转录病毒治疗HIV/AIDS病人免疫重建不良的回顾性研究[J].中国艾滋病性病，2020，26（2）：120-124.
[19] 刘宇超，李太生.慢性人免疫缺陷病毒感染者的免疫激活与免疫重建不全[J].协和医学杂志，2017，8（Z2）：210-214.
[20] 司扬扬，徐立然，孟鹏飞，等.中医药治疗艾滋病免疫重建不全研究进展[J].中医研究，2018，31（12）：66-69.
[21] 张国平，陈莉华，王丹妮，等.益艾康胶囊对HIV感染者免疫功能的影响[J].中医学报，2015，30（7）：925-927.
[22] 文彬，李秀娟，周小潇，等.清毒胶囊对HIV/AIDS患者HAART后不同基线CD4+人群免疫重建的影响[J].中华中医药学刊，2017，35（12）：3055-3057.
[23] 李璇，黄婷，文彬，等.壮药穴位贴敷配合HAART对30例老年艾滋病免疫重建不良病人疗效分析[J].中国艾滋病性病，2020，26（7）：753-756.
[24] Iba?觡ez GE，Fennie K，Larkey L，et al. A tai chi/qigong intervention for older adults living with HIV：a study protocol of an exploratory clinical trial [J]. Trials，2020， 21（1）：804.
[25] 罗伟生，王仕衍，黄瑞，等.中药复方制剂联合HAART对HIV/AIDS病人免疫重建的系统评价[J].中国艾滋病性病，2017，23（1）：28-32.
[26] 宋春荣，刘永刚，南然，等.高效抗逆转录病毒治疗联合健脾益肾方对无症状期艾滋病患者中医症候积分及CD4+T细胞数量的影响[J].中国中西医结合杂志，2021， 41（1）：46-49.
[27] 咸庆飞，刘颖，邹雯，等.温肾健脾颗粒对HAART后免疫重建不全艾滋病患者T淋巴细胞亚群的作用研究[J].中国中医基础医学杂志，2019，25（10）：1391-1392.
[28] 刘旭辉，陈媛媛，侯明杰，等.太芪培元颗粒联合HAART对HIV/AIDS患者免疫重建的影响[J].亚太传统医药，2020，16（05）：108-111.
[29] 苏琛，彭鑫，刘晶晶.培元胶囊联合HAART对艾滋病免疫重建不良的临床观察[J].中国艾滋病性病，2020， 26（1）：19-22.