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Effect of Banxia Xiexin Decoction combined with acupuncture in the treatment of chronic atrophic gastritis with syndrome of cold and heat complex#br# |
DING Liang1 XIAO Yan2▲ |
1.Department of Spleen and Stomach Disease, Suzhou Hospital of Integrated Traditional Chinese and Western Medicine, Jiangsu Province, Suzhou 215101, China;
2.Department of Acupuncture, Suzhou Hospital of Traditional Chinese Medicine, Jiangsu Province, Suzhou 215009, China |
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Abstract Objective To explore the effect of Banxia Xiexin Decoction combined with acupuncture in the treatment of chronic atrophic gastritis (CAG) with syndrome of cold and heat complex. Methods A total of 78 CAG patients with syndrome of cold and heat complex admitted to Suzhou Hospital of Integrated Traditional Chinese and Western Medicine, Suzhou Hospital of Traditional Chinese Medicine, Jiangsu Province from July 2020 to March 2021 were selected as the research subjects. According to random number table method, they were divided into control group (39 cases) and observation group (39 cases). The control group was treated with conventional Western medicine combined with acupuncture, and the observation group was treated with Banxia Xiexin Decoction on the basis of the control group, and both groups were treated for four weeks. The clinical efficacy, pepsinogenⅠ(PGⅠ) / pepsinogenⅡ (PGⅡ), interleukin-17 (IL-17), traditional Chinese medicine syndrome score and safety were observed between the two groups. Results After treatment, the total effective rate in the observation group was higher than that in the control group (P < 0.05). The PGⅠ/PGⅡ in the two groups was higher than that before treatment, which in the observation group was higher than that in the control group (P < 0.05). The serum IL-17 levels in the two groups were lower than that before treatment, which in the observation group was lower than that in the control group (P < 0.05). The traditional Chinese medicine syndrome symptom scores in the two groups were lower than that before treatment, which in the observation group was lower than that in the control group (P < 0.05), there was no significant difference in the incidence of adverse reactions between the two groups (P > 0.05). Conclusion Banxia Xiexin Decoction combined with acupuncture in the treatment of CAG patients with syndrome of cold and heat complex have a definite effect, which can reduce the body’s inflammation, and regulate PGⅠ/ PGⅡ balance, safe, and reliable.
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[1] 彭雪,韩俊,尹诗,等.针灸配合当归四逆汤治疗慢性萎缩性胃炎疗效观察[J].上海针灸杂志,2020,39(8):960-963.
[2] 董凡,邓银香,商竞宇,等.中医治疗慢性萎缩性胃炎研究近况[J].江苏中医药,2020,52(7):88-90.
[3] 韩晓江,杜锦辉,毕连宝,等.胃三针联合PPI三联疗法治疗幽门螺杆菌阳性慢性萎缩性胃炎疗效观察[J].上海针灸杂志,2020,39(1):11-14.
[4] 陈智昌,苏秋菊,邢建伟.穴位埋线联合温针灸治疗慢性萎缩性胃炎的疗效观察[J].中国临床医生杂志,2020,48(9):1119-1121.
[5] 宋青,刘震,黄达.中医药治疗慢性萎缩性胃炎的研究进展[J].首都医科大学学报,2019,40(3):479-482.
[6] 仁青东主,华青措,斗周才让,等.慢性萎缩性胃炎藏医四诊表象与G17及PGⅠ/PGⅡ的相关性研究[J].中华中医药杂志,2019,34(8):3736-3738.
[7] 金清龙,倪剑武.半夏泻心汤联合针灸治疗幽门螺杆菌阳性寒热错杂型慢性萎缩性胃炎疗效观察[J].中国药物与临床,2019,19(23):4085-4087.
[8] 王艳威,季杰,巩子汉,等.半夏泻心汤加减治疗慢性萎缩性胃炎脾胃湿热证临床研究[J].陕西中医,2020,41(4):499-501,537.
[9] 中华医学会消化病学分会.中国慢性胃炎共识意见(2017年,上海)[J].胃肠病学,2017,22(11):670-687.
[10] 郑筱萸.中药新药临床研究指导原则[M].北京:中国医药科技出版社,2002:361-362.
[11] 李金辉,李小青.萎胃汤联合西米替丁对慢性萎缩性胃炎模型大鼠胃黏膜修复及Wnt通路表达影响[J].四川中医,2019,37(8):37-41.
[12] 中国中西医结合学会消化系统疾病专业委员会.慢性萎缩性胃炎中西医结合诊疗共识意见(2017年)[J].中国中西医结合消化杂志,2018,26(2):121-131.
[13] 黄妙兴,李志坚,林沛玲,等.胃苏颗粒联合四联疗法治疗幽门螺杆菌阳性慢性萎缩性胃炎的疗效观察[J].中国医院用药评价与分析,2021,21(3):281-284.
[14] 黄晓映,曾耀明,何璠.健脾和胃方颗粒对脾虚气滞型慢性非萎缩性胃炎患者症状与心理及免疫状态的影响[J].中华全科医学,2020,18(7):1200-1203.
[15] 楼茜欣,唐梅文,唐燕,等.慢性萎缩性胃炎胃镜像与中医证型相关性研究进展[J].山东中医杂志,2020,39(8):887-890.
[16] 王萍,尹晓岚,张北华,等.近40年慢性萎缩性胃炎及胃癌前病变中医研究述评[J].中医杂志,2020,61(22):1943-1947.
[17] 杜立娟,孙敏,谈钰濛,等.半夏泻心汤对过氧化氢叔丁醇诱导的MIN6细胞凋亡及PI3K/AKT/FOXO1信号通路的影响[J].中医杂志,2020,61(1):63-67.
[18] 夏佩,何昊,马瑞,等.参芪消痞汤对慢性萎缩性胃炎癌前期病变胃黏膜修复作用和血管生成机制及血清p53、MDA、GSH-Px的相关影响[J].中国中西医结合消化杂志,2021,29(1):19-23.
[19] 许爱丽,唐彬,王源,等.应用整合药理学方法探讨半夏泻心汤治疗慢性萎缩性胃炎的作用机制[J].北京中医药,2019,38(5):407-412.
[20] 王丹,裴斯彪,唐志立,等.健脾促愈汤治疗慢性萎缩性胃炎的临床疗效及对胃动力和炎症因子的影响[J].四川中医,2020,38(4):111-114.
[21] 闫小妮,刘瑜佳,李红霞,等.复方乌贝方治疗慢性浅表性胃炎的疗效及对胃镜像指标、血清EGF、GAS、SS和Hp阴转率的影响[J].四川中医,2019,37(2):116-118.
[22] 魏家,朱春龙.胃炎方对脾胃湿热型慢性萎缩性胃炎的疗效及对患者IFN-β、自由基的影响[J].四川中医,2020, 38(3):116-119.
[23] 马耿,张丽贤.标准四联疗法对幽门螺杆菌阳性慢性萎缩性胃炎患者血清GH、PGⅠ、PGⅡ、IL、TGF-β1水平及预后的影响分析[J].中国医学前沿杂志:电子版,2019, 11(1):79-82.
[24] 雷洪军,潘金,曹丽鹏,等.血清胃泌素-17、胃蛋白酶原Ⅰ、胃蛋白酶原Ⅱ、同型半胱氨酸在萎缩性胃炎患者表达的临床意义[J].实用医院临床杂志,2020,17(5):135-138.
[25] 魏晨阳,王倩.中医药治疗慢性萎缩性胃炎临床用药规律[J].中医学报,2020,35(9):2031-2034. |
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