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| Application of intracavity radiofrequency closure in the treatment of varicose of great saphenous vein#br# |
| TENG Hale1 CUI Shuisen1 LI Zhijian1 DONG Jiande1 CAI Hongli2 HUANG Jinhong1 |
1.Department of Cardiovascular Surgery, Capital Medical University Electric Power Teaching Hospital, Beijing 100073, China;
2.Health Management Center, Capital Medical University Electric Power Teaching Hospital, Beijing 100073, China |
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Abstract Objective To evaluate the value of intracavity radiofrequency closure in the treatment of varicose of great saphenous vein. Methods A total of 126 patients with varicose of great saphenous vein admitted to Electric Power Teaching Hospital of Capital Medical University from June 2019 to June 2020 were selected. They were divided into control group and observation group (63 cases in each group) by random number table method. The control group received traditional surgery, and the observation group received intracavity radiofrequency closure. The therapeutic effect, perioperative indicators, and hemodynamic indexes 12 hours after surgery were compared between the two groups. The levels of inflammatory factors were compared between the two groups before surgery and one week after surgery, and the venous clinical severity score were compared between the two groups before surgery and six months after surgery. The two groups were followed up for one year to observe the incidence of adverse reactions. Results The amount of intraoperative blood loss in the observation group was lower than that in the control group, and the surgery time, postoperative time out of bed, and hospital stay were shorter than those in the control group, with statistical significances (P ＜ 0.05). There were no significant differences in percutaneous arterial oxygen saturation, heart rate, and mean arterial pressure between the two groups at 12 hours after surgery (P ＞ 0.05). Serum levels of tumor necrosis factor-α, interleukin-6, and matrix metalloproteinase-13 in two groups one week after operation were lower than those before surgery, and the observation group was lower than the control group, the differences were statistically significant (P ＜ 0.05). The venous clinical severity scores at six months after surgery was lower than that before surgery, and the observation group was lower than the control group, the differences were statistically significant (P ＜ 0.05). There was no significant difference in treatment effect between the two groups (P ＞ 0.05). There was no significant difference in the incidence of deep vein thrombosis, subcutaneous hematoma, phlebitis, saphenous nerve injury, pigmentation, and varicose recurrence between the two groups (P ＞ 0.05). The incidences of wound infection/poor healing and thigh hematoma in the observation group were lower than those in the control group, and the differences were statistically significant (P ＜ 0.05). Conclusion Intracavity radiofrequency closure for the treatment of varicose of great saphenous vein can effectively relieve the symptoms of lower limb veins and reduce the inflammatory state of the body, with less surgical trauma, less intraoperative bleeding, less complications, precise clinical efficacy and high safety.
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