miR-150与肺部疾病关系的研究进展

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Abstract With the aggravation of air pollution and the increase of harmful factors in the environment, the prevalence of respiratory diseases has been increasing year by year in recent years. Studies have shown that micrornas (miRNA) are involved in many pathophysiological processes of the body by regulating gene expression. miR-150 is a member of miRNA family, it has been proven to be associated with lung cancer, acute lung injury, pulmonary fibrosis, pulmonary hypertension, chronic obstructive pulmonary disease, pleural effusion and so on. Up-regulation or down-regulation of miR-150 can effectively regulate the biological process of these diseases, it is suggested that miR-150 is closely related to the occurrence, development and prognosis of the above-mentioned diseases, may provide new targets for the diagnosis and treatment of respiratory diseases. This paper will review the research progress on the relationship between miR-150 and lung diseases.

Key words： MicroRNA Lung disease Gene regulation miR-150

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	CAI Qian1 CHEN Sirui2 ZHU Yingqun1

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CAI Qian1 CHEN Sirui2 ZHU Yingqun1. Research progress on the relationship between miR-150 and pulmonary diseases#br#[J]. 中国医药导报, 2021, 18(34): 51-54.

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https://www.yiyaodaobao.com.cn/EN/ OR https://www.yiyaodaobao.com.cn/EN/Y2021/V18/I34/51

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