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| Clinical study of interventional therapy for acute lower extremity arterial embolism |
| HE Jingliang LIANG Zhihui LI Liang LIU Jinglei |
| Department of Vascular Surgery, PLA Bethune International Peace Hospital, Hebei Province, Shijiazhuang 050082, China |
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Abstract Objective To investigate the clinical efficacy of interventional therapy for acute lower extremity arterial embolism. Methods From June 2016 to June 2017, in PLA Bethune International Peace Hospital, 60 patients with acute arterial embolism of lower extremity were selected, according to the treatment methods, they were divided into two groups, 30 cases in the control group were treated with large cavity catheter sucking thrombus, and 30 cases in the experiment group were treated with large cavity catheter sucking thrombolytic thrombolysis plus catheter thrombolytic therapy. The treatment effect, prothrombin time (PT), activated partial thromboplastin time (APTT), fibrinogen (FIB) and D-Dimer (D-D) level of the two groups were compared, and the recurrence rate and amputation rate of the two groups were observed. Results After treatment, the total effective rate of experiment group was significantly higher than that of control group, the difference was statistically significant (P < 0.05). After treatment, the levels of APTT and PT in the two groups were higher than those before treatment, and those in the experiment group were significantly higher than those of control group, the differences were statistically significant (P < 0.05), and the levels of FIB and D-D in the two groups were significantly lower than those before treatment, and those in the experiment group were significantly lower than those of control group, the differences were statistically significant (P < 0.05). After treatment, the incidence of embolic recurrence in the experiment group was lower than that of control group, the difference was statistically significant (P < 0.05). There was no significant difference in amputation rate between the experiment group and control group (P > 0.05). Conclusion The clinical effect of large cavity catheter suction thrombolysis plus catheter thrombolysis for patients with acute lower extremity arterial embolization is remarkable, and the complications are few, the clinical effect is better than that of the simple use of large cavity catheter suction thrombolytic therapy, and it can be popularized.
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