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| Clinical effect of Paclitaxel combined with bronchial endoscopy intervention in treatment of benign hypertrophic scar stenosis |
| GUO Peng |
| Department of Oncology, Zhejiang Tumor Hospital, Zhejiang Province, Hangzhou 310022, China |
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Abstract Objective To analyze the clinical effect of Paclitaxel combined with bronchial endoscopy intervention in the treatment of benign hypertrophic scar stenosis. Methods From May 2014 to May 2016, in Zhejiang Tumor Hospital, 40 patients with hypertrophic scar stenosis were selected, they were divided into Paclitaxel combined with bronchial endoscopy intervention treatment group (combined treatment group, 20 cases) and single bronchial endoscopy intervention treatment group (single treatment groups, 20 cases), sectional areas, shortness of breath, dyspnea index scores, pulmonary functions, clinical efficacy, incidences of adverse reactions of the two groups were statistically analyzed. Results compared with single group, in combined group, the airway diameter and cross-sectional area were significantly higher (P < 0.05), the dyspnea score was significantly lower (P < 0.05), the proportions of dyspnea grade 0, grade Ⅰwere significantly higher (P < 0.05), the proportions of dyspnea grade Ⅲ, grade Ⅳ were significantly lower (P < 0.05), the total treatment efficiency was significantly higher than the single treatment group (P < 0.05), the FEV1, VC, MVV, MMEF were significantly higher (P < 0.05). Conclusion The clinical effect of Paclitaxel combined with bronchial endoscopy intervention in the treatment of benign hypertrophic scar stenosis is better than single bronchial endoscopy intervention treatment.
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