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| Analysis of neurocognitive impairment characteristic in alcohol-dependent patients with aggressive behavior |
| ZHOU Xiafeng1 ZHOU Xuhui1 GUO Yujun1 YANG Jun1 HUANG Saiping1 ZHANG Li2▲ |
1.Department of Psychiatry, Brain Hospital of Hu′nan Province, Changsha 410007, China；
2.Department of Psychiatry, the Second Xiangya Hospital of Central South University, Hu′nan Province, Changsha 410000, China |
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Abstract Objective To study the characteristics of neurocognitive impairment in alcohol-dependent patients with aggressive behavior. Methods 100 patients with alcohol dependence were enrolled in Brain Hospital of Hu′nan Province from January 2015 to January 2016. The patients were divided into two groups according to the explicit behavior attack scale. The 50 patients with aggressive behavior were considered as the observation group, 50 patients without aggressive behavior were considered as the control group. According to the Wechsler adult intelligence scale, Stroop test and Wisconsin card sorting test, the cognitive function impairment, memory function, attention and executive function of the two groups were compared. Results The mean score of Wechsler adult intelligence scale and memory quotient in the observation group were significantly lower than those of the control group, the differences were statistically significant (P < 0.05). The ST-CW test score and the ST-C test score in the observation group were significantly lower than those of the control group, the differences were statistically significant (P < 0.05). The working memory capacity score and the cognitive transfer ability score of the observation group were significantly lower than those of the control group, the differences were statistically significant (P < 0.05). Conclusion Alcohol-dependence can impair the cognitive function of the patients. The neurocognitive dysfunction of alcohol-dependence patients with aggressive behavior is more serious. Most patients show the reduction of memory function, attention and executive function. Cognitive impairment of consciousness is also an important factor that leads to aggressive behavior in patients.
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