|
|
|
| Clinical effect of integrated traditional Chinese and western medicine therapy in the treatment of chronic pelvic inflammatory disease and its impact on related inflammatory factors and hemorheology |
| FENG Wei1 MA Jianwen2 LYU Ruihuang1 |
1.Department of Pharmacy, Urumqi Maternal and Child Health Hospital, Xinjiang Uygur Autonomous Region, Urumqi 830001, China;
2.Department of Pharmacy, Affiliated Hospital of Traditional Chinese Medicine of Xinjiang Medical University, Xinjiang Uygur Autonomous Region, Urumqi 830001, China |
|
|
|
Abstract Objective To investigate the clinical effect of integrated traditional Chinese and western medicine therapy on chronic pelvic inflammatory disease and its impact on related inflammatory factors and hemorheology. Methods Sixty-two patients with chronic pelvic inflammatory disease treated in Urumqi Maternal and Child Health Hospital from January 2016 to January 2017 were randomly divided into control group (antibiotic intravenous drip) and experimental group (antibiotic combined with traditional Chinese medicine decoction) by random number table, with 31 cases in each group. The TCM syndrome effect of the two groups was compared, and the levels of tumor necrosis factor-α (TNF-α), high sensitive C-reactive protein (hs-CRP), interleukin-2 (IL-2) and the hemorheology changes of the two groups before and after treatment were observed. Results After treatment, the TCM syndrome effect in the experimental group was better than that in the control group (P ＜ 0.05); the levels of whole blood viscosity, plasma viscosity, haematocrit and erythrocyte sedimentation rate in the two groups were significantly decreased compared with before treatment (P ＜ 0.05), and the experimental group was significantly lower than those of control group (P ＜ 0.05); the levels of TNF-α, hs-CRP and IL-2 of two groups were significantly improved compared with before treatment (P ＜ 0.05), and the improvement of the experimental group was significantly better than the control group (P ＜ 0.05). Conclusion The clinical effect of traditional Chinese medicine decoction combined with antibiotic in the treatment of chronic pelvic inflammatory disease is significant, which can effectively alleviate the inflammatory reactions and improve the indexes of hemorheology, and it has high clinical application value.
|
|
|
|
|
|
[1] 吕晓君，何开勇，潘望平，等.赤母妇炎宁胶囊治疗慢性盆腔炎的实验研究[J].中国医药导报，2015，12（4）：23-28.
[2] 王月利.中西医结合治疗慢性盆腔炎的临床分析[J].辽宁中医杂志，2013，40（10）：2080-2081.
[3] 王瑞雪，杨云，张丽中.盆腔炎病原菌分布及药敏情况分析[J].山西医药杂志，2014，43（17）：2085-2086.
[4] 陆珏瑾.盆腔炎性疾病的病因及诊治进展[J].中国生育健康杂志，2014，20（5）：337-340.
[5] 王艳华.妇科千金片联合中药灌肠治疗慢性盆腔炎的疗效及对血液流变学和炎性因子水平的影响[J].河北医药，2015，37（20）：3076-3078.
[6] 张宁，朱慧芳.慢性盆腔炎中医治疗浅谈[J].陕西中医学院学报，2013，36（2）：11-12.
[7] 张双，高月平.慢性盆腔炎的中西医研究进展[J].河南中医，2014，34（3）：497-499.
[8] 乐杰.妇产科学[M].6版.北京：人民卫生出版社，2005.
[9] 郑筱萸.中药新药临床研究指导原则[M].北京：中国医药科技出版社，2002.
[10] 刘华生.中医诊断学[M].6版.北京：清华大学出版社，2003.
[11] 张玉珍.中医妇科学[M].7版.北京：中国中医药出版社，2002.
[12] 林慧敏，王英，潘一红.中医辨证联合抗生素治疗慢性盆腔炎临床疗效分析及对患者血液流变学水平的影响[J].中华中医药学刊，2015，33（12）：3030-3032.
[13] 周小琳.65例慢性盆腔炎中西医结合临床治疗观察[J].中国中医基础医学杂志，2013，19（2）：216-217.
[14] 陈鸿，赵煜，赖玉琴，等.银藤合剂配合温针灸治疗湿热瘀结型慢性盆腔炎92例临床疗效探讨[J].中国现代医学杂志，2014，24（15）：66-70.
[15] 徐祥梅，何晓燕.中西医结合治疗盆腔炎性疾病临床疗效观察及安全性评价[J].中华中医药学刊，2015，33（4）：1017-1019.
[16] 陈海霞，谷晓芬，刘雁峰.慢性盆腔炎的中医药治疗概况[J].现代中医临床，2013，20（5）：40-43.
[17] 张合民，魏静，欧晓欣，等.中西医结合治疗129例慢性盆腔炎临床疗效研究[J].中国现代医生，2015，53（25）：112-114.
[18] 王明环.中西医结合治疗慢性盆腔炎62例的效果观察[J].中外医学研究，2016，14（24）：108-110.
[19] 王丽，刘金星，张师前.蒲地蓝消炎口服液治疗慢性盆腔炎的临床观察[J].中华医院感染学杂志，2015，25（22）：5169-5171.
[20] 张利.白芍的药理作用及现代研究进展[J].中医临床研究，2014，6（29）：25-26.
[21] 刘春泥，廖鑫波.中西医结合治疗瘀阻胞宫型慢性盆腔炎的临床疗效分析[J].中国现代医生，2016，54（17）：54-56.
[22] 余露军.中西医结合治疗妇科慢性盆腔炎38例观察[J].中外医学研究，2016，14（36）：151-152.
[23] 杨琪伟，杨莉，熊爱珍，等.赤芍与白芍抗血小板凝集作用的UPLC-MS代谢组学初步研究[J].中国中药杂志，2011，36（6）：698-701.
[24] 吴苗敏，韩璐，刘娜.中药三联疗法治疗慢性盆腔炎患者临床疗效及对血液流变学的影响研究[J].中国中医基础医学杂志，2014，20（5）：658-659. |
|
|
|
