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| Influencing factor of clinical progress and prognosis of anterior choroidal artery blood supply area infarction |
| TONG Yanna CHENG Zhe DUAN Honglian SONG Zhaohui ZHANG Weidong DU Mingyan MENG Fanhua GENG Xiaokun▲ |
| Department of Neurology, Beijing Luhe Hospital, Capital Medical University, Beijing 101100, China |
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Abstract Objective To explore the possible mechanism and the prognosis of progressive infarction in the anterior choroidal artery (AChA) territory. Methods 113 patients with infarction in the AChA territory, admitted to Beijing Luhe Hospital from June 2014 to February 2016, confirmed by brain computed tomography (CT) or magnetic resonance imaging (MRI) were retrospectively analyzed. All the patients enrolled were divided into two groups: progressive infarction group (49 cases) and no progressive infarction group (64 cases). Cerebral infarction related risk factors were collected and cerebral vascular evaluations were done in all the patients. Then cerebral infarction related risk factors and cerebral vascular conditions were compared between two groups in order to explore the causes and mechanisms of the progressive infarction. All the patients were followed up for 6 months and the prognosis were compared between two groups. Results Patients with hypertension, diabetes and hyperlipidemia (known as "three high disease") were obviously more in the progressive infarction group than in the no progressive infarction group (P = 0.039). Patients with heart disease were also significantly more in the progressive infarction group (P = 0.027). The national institute of health stroke scale (NIHSS) score of patients in the progressive infarction group were higher at discharge, and patients in the progressive infarction group had worse prognosis than those in no progressive infarction group. Conclusion Neurological deterioration is frequent in the AChA infarction. "Three high disease", heart disease and carotid atherosclerotic plaque and (or) stenosis are associated with the progress of AChA infarcts. Patients with progressive AChA infarction has worse prognosis than those with no progressive AChA infarction.
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