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| Medication adherence and its influencing factors among the hepatitis B patients in the middle and later period of pregnancy |
| DU Xiaona TIAN Hongwei WU Huiping DONG Jiawei LIU Xiaojing DONG Zhenghong |
| Department of Obstetrics and Gynecology, the Fifth Hospital of Shijiazhuang City, Hebei Province, Shijiazhuang 050021, China |
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Abstract Objective To investigate the status and influencing factors of medication adherence among hepatitis B patients in the middle and later period of pregnancy. Methods A total of 124 hepatitis B patients in the middle and later period of pregnancy treated in the Fifth Hospital of Shijiazhuang City from April 2016 to April 2017 were recruited. Medication adherence was assessed by the Morisky Medication Adherence Questionnaire (MAQ). The main measuring instruments included the general Characteristics Questionnaire, the hepatitis B knowledge questionnaire and the Medication belief scale. Multiple Logistic regression analysis was used to analyze the influencing factors of medication adherence of hepatitis B patients. Results The score of overall hepatitis B related knowledge, the Medication belief and medication adherence were fair to middling, and the patients with good compliance accounted for 60.5%(75 cases). Multivariate Logistic regression analysis showed that education level (OR = 0.578, 95%CI: 0.104-0.877), parents have or no hepatitis B (OR = 0.392, 95%CI: 0.177-0.631), diagnosis time of hepatitis B (OR = 3.998, 95%CI: 1.188-5.285), hepatitis B related knowledge (OR = 0.746, 95%CI: 0.389-0.847), medication beliefs (OR = 0.787, 95%CI: 0.259-0.977) were influencing factors for medication adherence (P < 0.05). Conclusion Health care workers should combine the influencing factors of medication adherence to carry out targeted health education, so as to improve their medication adherence and reduce the vertical transmission rate of hepatitis B.
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