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| Clinical effect of neuroendoscope transsphenoidal surgery in the treatment of giant invasive pituitary adenoma |
| QU Zhe1 TIAN Jun1 HU Yuhong2 SU Baiyu3 WANG Kun1 TAN Haopeng1 LI Jianhua1 |
1.Department of Neurosurgery, the First Hospital of Shijiazhuang, Hebei Province, Shijiazhuang 050000, China;
2.Department of Medical Insurance, the First Hospital of Shijiazhuang, Hebei Province, Shijiazhuang 050000, China;
3.Department of Endocrine, the First Hospital of Shijiazhuang, Hebei Province, Shijiazhuang 050000, China |
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Abstract Objective To study the clinical effect of endoscopic transsphenoidal surgery in the treatment of giant invasive pituitary adenoma. Methods A total of 76 patients with giant invasive pituitary adenoma admitted to the First Hospital of Shijiazhuang from March 2015 to January 2017 were selected. They were divided into observation group (39 cases) and control group (37 cases) according to digital random table method. The observation group was treated with neuroendoscopic transsphenoidal surgery, and the control group was treated with transcranial microscopy. The patients in the two groups were followed up for 1 year, and the clinical indicators, such as total cut rate, postoperative symptom remission rate, postoperative complications rate, tumor residual rate and recurrence rate were compared. Results The operation time and postoperative hospitalization time of the observation group were shorter than those of the control group, the intraoperative blood loss was less than the control group, and incidence of postoperative complications, tumor residual rate and recurrence rate were lower than those of the control group, while the total incision rate and postoperative symptom remission rate were higher than those of the control group, with statistically significant differences (all P < 0.05). Conclusion Neuroendoscopic transsphenoidal surgery has obvious clinical efficacy in the treatment of giant invasive pituitary adenoma, which can effectively shorten the operation time, reduce the amount of bleeding, promote the early recovery of patients, and effectively reduce the incidence of postoperative complications, as well as the residual rate and recurrence rate of tumors, which are safe and worthy of clinical application.
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| Fund:河北省石家庄市科学技术研究与发展指导计划项目（171461563）。 |
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