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| Study on pathogenic factors of ischemic stroke patients and primary prevention method |
| LIU Hua ZHOU Yuanji XIA Yun TANG Haiyan ZHAO Xuan JIANG Yaxuan CHEN Xiaomei HUO Chunnuan▲ |
| Ward Ⅰ, Department of Neurology, Chinese PLA General Hospital, Beijing 100853, China |
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Abstract Objective To explore the risk factors of patients with stroke and the primary prevention methods, in order to provide references for the clinical treatment and nursing. Methods From February 2016 to February 2017, in Department of Neurology, Chinese PLA General Hospital ("our hospital" for short), 80 stroke patients were selected as cases group, at the same period, 100 non-stroke patients were selected as control group. Through literature review made possible factors associated with the disease: routine physical examination, smoking, excessive alcohol consumption, improper diet, excessive waist-to-hip ratio, physical exercise, mental stress and depression, normal communication with children, normal social interaction, hypertension, diabetes, basic heart disease, hyperlipidemia. The case-control study was conducted on the occurrence of related factors in the two groups, and the difference comparison was made using the odds ratio (OR) and chi-square test; combined with the results of case-control analysis, further exposure factors and Logistic regression analysis were performed. Results There was no statistically significant difference between the two groups in routine physical examination, normal social intercourse, diabetes and hyperlipidemia (P < 0.05), while there were significant differences in other factors (P < 0.05). The results of Logistic regression analysis showed that physical exercise, normal communication with their children were protective factors (P < 0.05), and smoking, excessive alcohol consumption, improper diet, excessive waist-to-hip ratio, mental stress and depression, hypertension, and underlying heart disease were risk factors (P < 0.05). Conclusion Smoking, excessive alcohol consumption, improper diet, excessive waist-to-hip ratio, mental stress and depression, hypertension, and underlying heart disease are risk factors for stroke. The primary prevention method for stroke patients can be found according to the cause of the disease.
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