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Surveillance and analysis of multi-drug resistant bacteria infections in AIDS patients in traditional Chinese medicine hospitals |
NI Wei YANG Liu LIU Guangzhong |
Department of Clinical Laboratory, Hubei Provincial Hospital of Traditional Chinese Medicine Hubei Provincial Academy of Traditional Chinese Medicine, Hubei Province, Wuhan 430074, China |
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Abstract Objective To investigate the differences of composition and distribution of multidrug-resistant bacteria in patients with HIV/AIDS between Hubei Provincial Hospital of Traditional Chinese Medicine ("our hospital" for short) and western hospitals, and to explore the existing problems in the prevention of multi-drug resistant bacteria hospital infection in traditional Chinese medicine hospitals and put forward effective measures for reference. Methods A total of 852 samples of the AIDS patients diagnosed with hospital infection in our hospital from January 2008 to December 2017 were isolated and cultured, bacterial identification and drug sensitivity analysis were conducted, and personal data were collected. Results The detection rate of multidrug-resistant bacteria in our hospital was 51.17%. The lower respiratory tract (60.09%) was the main infected part, followed by blood system (19.95%) and urinary system (14.91%). HIV/AIDS infection in patients with multiple drug-resistant bacteria were mainly Pseudomonas aeruginosa (25.00%), Escherichia coli (20.18%), coagulase negative staphylococcus (17.89%), Klebsiellapneumoniae (10.09%), Acinetobacterbaumannii (8.95%), Staphylococcus aureus (8.03%), Candida albicans (6.88%). Conclusion Compared with Western hospitals, the detection rate of multidrug-resistant bacteria is lower in our hospital. However, it is necessary to strengthen the monitoring of multidrug-resistant bacteria spectrum, attach importance to the combination therapy of Chinese and Western medicine, implement the classification management system of antibacterial drugs, so as to effectively control the occurrence of multiple drug-resistant bacteria hospital infection of AIDS patients.
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