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| Clinical observation of Guipi Decoction in the treatment of arrhythmia |
| SHU Huiwen1 JI Yaming2 LI Yuhuan3 |
1.Outpatient Department, Beijing Xiaotangshan Hospital, Beijing 102211, China;
2.Department of TCM Pharmacy, Beijing Xiaotangshan Hospital, Beijing 102211, China;
3.Department of Rehabilitation, Beijing Xiaotangshan Hospital, Beijing 102211, China |
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Abstract Objective To observe the clinical effect of modified Guipi Decoction in the treatment of arrhythmia. Methods Sixty patients with arrhythmia in Outpatient Department of TCM, Beijing Xiaotangshan Hospital from October 2014 to June 2017 were collected, and 60 patients were divided into treatment group and control group according to different treatment methods, with 30 cases in each group. The treatment group was treated with basic western medicine + Guipi Decoction, the control group was treated with basic western medicine, the course was 4 weeks. The clinical efficacy, the 24-hour dynamic electrocardiogram efficacy, the changes of TCM symptom scores before and after treatment and the TCM symptom score efficacy between the two groups were compared, and the drug safety of the two groups was observed. Results In the clinical effect, the total effective rate was 93.3% in the treatment group and 73.3% in the control group, the difference of the total effective rate between the two groups was statistically significant (P ＜ 0.05). In the 24-hour dynamic electrocardiogram efficacy, the total effective rate was 90.0% in the treatment group and 66.7% in the control group, the difference of the total effective rate between the two groups was statistically significant (P ＜ 0.05). In the TCM symptom scores, the TCM symptom scores in the treatment group after treatment were lower than those before treatment (P ＜ 0.05), which were lower than those of control group, the difference between the two groups was statistically significant (P ＜ 0.05). In the TCM symptom scores efficacy, the total effective rate was 96.7% in the treatment group and 76.7% in the control group, the difference of the total effective rate between the two groups was statistically significant (P ＜ 0.05). There were no significant differences in liver function, renal function, blood routine, urine routine, regular routine before and after treatment in both groups. Conclusion Guipi Decoction can effectively relieve myocardial ischemia in patients with arrhythmia and improve clinical symptoms.
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