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Treatment of chronic obstructive pulmonary disease combined with sleep apnea syndrome based on "deficiency-stasis-toxin" |
ZHANG Wenjiang1 HOU Chunyan2 FAN Changzheng1 |
1.Department of Respiratory, Xiyuan Hospital, China Academy of Chinese Medical Sciences, Beijing 100091, China;
2.Center of Cardiovascular Disease, Xiyuan Hospital, China Academy of Chinese Medical Sciences, Beijing 100091, China |
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Abstract According to the development of pathophysiology of chronic obstructive pulmonary disease combined with sleep apnea syndrome in modern medical science, and understanding of the etiology of "toxin" evil in the basic theory of traditional Chinese medicine (TCM), the deficiency, toxin and blood stasis of TCM pathogenesis are involved in the disease. This article focuses on the interaction of "deficiency", "blood stasis" and "toxin" in the process of occurrence and development of the disease, and exploration of the corresponding effective treatment and prescriptions. It is significant to recognize and stress the interaction of them in pathogenicity so as to enrich TCM etiology and improve TCM clinical efficacy in the treatment of chronic obstructive pulmonary disease combined with sleep apnea hypopnea syndrome.
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[1] He ZM,Yang JJ. Overlap syndrome-sleep apnea syndrome in patients with chronic obstructive pulmonary disease [J]. Int J Respir,2009,29(5):287.
[2] O'Donoghue FJ,Catcheside PG,Ellis EE,et al. Sleep hypoventilation in hypercapnic chronic obstructive pulmonary disease:prevalence and associated factors [J]. Eur Respir J,2003,21(6):977-984.
[3] Valipour A,Lavie P,Lothaller H,et al. Sleep profile and symptoms of sleep disorders in patients with stable mild to moderate chronic obstructive pulmonary disease [J]. Sleep Med,2011,12(4):367-372.
[4] Mayos M,Hernandez-Plozo L,Farre AM,et al. The effect of nocturnal oxygen therapy in patients with sleep apnea syndrome and chronic airflow limitation [J]. Arac Brononeumol,2001,37(2):65-68.
[5] 曹邦卿,薛汉荣,喻强强.慢性阻塞性肺疾病稳定期中医证候与防御素相关性的理论探讨[J].世界中西医结合杂志,2015,10(3):422-423.
[6] Ganz T. Defensins:antimicrobial peptides of innate immunity [J]. Nat Rev Immunol,2003,3(9):710-720.
[7] Pazgier M,Hoover DM,Yang D,et al. Human beta-defensins [J]. Cell Mol Life Sci,2006,63(11):1294-1313.
[8] Liao Z,Dong J,Hu X,et al. Enhanced expression of human β-defensin 2 in peripheral lungs of patients with chronic obstructive pulmonary disease [J]. Peptides,2012, 38(2):350-356.
[9] 高蔚,翁婷,孟文书.慢性阻塞性肺疾病患者诱导痰中β-防御素2水平及其与NF-κB的相关性[J].实用医学杂志,2011,27(24):4401-4403.
[10] Garvey JF,Taylor CT,McNicholas WT. Cardiovascular disease in obstructive sleep apnea syndrome:the role of intermittent hypoxia and inflammation [J]. Eur Respir J,2009,33(5):1195-1205.
[11] 宋海峰,李南方.炎症因子与阻塞性睡眠呼吸暂停综合征的睡眠结构紊乱[J].医学综述,2009,15(9):1301-1303.
[12] Martin RJ,Bartelson BL,Smith P,et al. Effect of ipratropium bromide treatment on oxygen saturation and sleep quality in COPD [J]. Chest,1999,115(5):1338-1345.
[13] 覃家盟.COPD合并阻塞性睡眠呼吸低通气综合征的临床分析[J].中外妇儿健康,2011,19(6):21-22.
[14] Young T,Palta M,Dempsey J,et al. The occurrence of sleep-disordered breathing among middle-aged adults [J]. N Engl J Med,1993,328(17):1230-1235.
[15] Jelic S. Diagnostic and therapeutic approach to coexistent chronic obstructive pulmonary disease and obstructive sleep apnea [J]. Int J Chron Obstruct Pulmon Dis,2008,3(2):269-275.
[16] 沈宁,邱梦茹,朱雪,等.睡眠呼吸暂停低通气综合征中医辨治思路[J].中医杂志,2015,56(4):297-299.
[17] 张文江,史大卓.瘀毒阻络——慢性阻塞性肺疾病的病因病机初探[J].世界中医药,2012,7(1):7-8.
[18] 苗青,张旭丽,林佳阳,等.80例睡眠呼吸暂停综合征患者中医证型分析[J].中医杂志,2008,49(11):989-991.
[19] 邝浩丹,骆仙芳.王会仍辨治慢性阻塞性肺疾病合并阻塞性睡眠呼吸暂停综合征经验探析[J].浙江中医药大学学报,2013,37(12):1397-1399.
[20] 陈佑林,李珊,赵阳红.名老中医罗泽伦经验方“七味消毒饮”治验数则[J].贵阳中医学院学报,2007,29(2):13-14.
[21] 李娜,姚月华,郑向艺,等.基于中医传承辅助系统治疗阻塞性睡眠呼吸暂停综合征方剂组方规律分析[J].世界睡眠医学杂志,2015,2(1):49-53. |
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