|
|
|
| Effect research of five-note therapy in the treatment of acute earlier acute stage of migraine with syndrome of liver Yang ascending hyperactively |
| LYU Weihua TI Guixiang LYU Xia LYU Pin▲ |
| Preventive Medicine Department, Guang′anmen Hospital, China Academy of Traditional Chinese Medicine, Beijing 100053, China |
|
|
|
Abstract Objective To observe the clinical effect of five-note therapy on acute earlier acute stage of migraine with syndrome of liver Yang ascending hyperactively. Methods 90 patients with acute earlier acute stage of migraine with syndrome of liver Yang ascending hyperactively in Guang′anmen Hospital, China Academy of Traditional Chinese Medicine from June 2015 to April 2017 were selected, and they were divided into two groups according to random number table, with 45 cases in each group. The control group was treated with acupuncture at regular acupoints for 30 min; the treatment group was treated with five-note therapy on the base of control group for 30 min. After treatment, headache VAS score of 1 hour, 2 hours, 4 hours and 24 hours between two groups were observed and curative effect of two groups were evaluated. The levels of serum 5-HT and CGRP were compared between the two groups. Adverse reactions were observed between the two groups. Results After treatment, the total efficiency of control group was 80.0%, 95.6% in the treatment group, the difference was statistically significant between the treatment group and control group (P < 0.05). After treatment, The VAS scores at each time point between the two groups were significantly lower than those before treatment, with statistically significant difference (P < 0.05), but there was no significant difference between the two groups (P > 0.05). There were no obvious changes in blood and urine routine, liver and kidney function before and after treatment between the two groups (P > 0.05). After treatment, the serum level of 5-HT in the two group were significantly higher than those before treatment, the levels of CGRP were significantly lower than those before treatment, with statistically significant difference (P < 0.05), and after treatment, the levels of serum 5-HT and CGRP of treatment group were significantly better than those of the control group, with statistically significant difference (P < 0.05). There were no obvious adverse reactions among the three groups. Conclusion Five-note therapy combined with conventional acupuncture can improve the acute earlier acute stage of migraine with syndrome of liver Yang ascending hyperactively, and have no obvious adverse reaction, high safety, and is worthy of popularization and application.
|
|
|
|
|
|
[1] 关竹洋. 针刺头三针治疗肝阳上亢型偏头痛的临床研究[D].长春：长春中医药大学，2015.
[2] 魏丹.针刺透穴法治疗肝阳上亢型偏头痛疗效观察[J]. 北京中医药，2012，31（1）：46-48.
[3] 朱明瑾.肝阳上亢型偏头痛中医症状特征及相关因素分析[D].济南：山东中医药大学，2009.
[4] 赵廉政，陈以国.传统中医五音疗法的研究进展[J].中华中医药杂志，2016，31（11）：4666-4668.
[5] 王卓，朱萍.五音入五脏——中医五音疗法探析[J].中医药文化，2015，10（5）：57-61.
[6] 张杰，徐芳，杜渐，等.中医五音疗法探析[J].长春中医药大学学报，2011，27（5）：702-704.
[7] 邓丽影，杜彦辉，冯加纯，等.中国偏头痛诊断治疗指南[J].中国疼痛医学杂志，2011，17（2）： 65-86.
[8] 郑筱萸.中药新药临床研究指导原则（试行）[M].北京：中国医药科技出版社，2002.
[9] 邓竹青. 针刺少阳经特定穴对偏头痛急性发作期的临床评价研究[D].成都：成都中医药大学，2012.
[10] 钟枢才.杵针学[M].北京：中国中医药出版社，2006.
[11] 孙增华，杨玉金.偏头痛诊断、疗效评定标准意见[J].中风与神经疾病杂志，1995，12（2）：110-112.
[12] 周仲瑛，蔡淦.中医内科学[M].2版.北京：人民卫生出版社，2010.
[13] 国家食品药品监督管理局.中药新药临床研究指导原则（试行）[M].北京：中国医药科技出版社，2003.
[14] 董兰真，蒲圣雄，周冀英. 偏头痛与神经源性炎症的研究进展[J]. 重庆医学，2015，44（08）：1126-1128.
[15] Williamsom DJ，Hargreaves RJ，Hill RG，et al.Intravital microscope studies on the effects of neu-rokinin agonists and calcitonin gene related peptide on dural vessel diameter in the anaesthetized rat [J]. Cephalalgia，1997，17（4）：518-524.
[16] 吕艳斐. 电针对偏头痛模型大鼠腺苷A_1受体及信号转导通路的作用机制研究[D].济南：山东中医药大学，2016.
[17] 吴玉娟，郑盛惠，吴杰倩，等.中医五音疗法在慢性疲劳综合征患者中的应用[J].现代临床护理，2013.12（12）：40.
[18] 刘振寰，张丽红，赵勇.五行体感音乐对痉挛型脑性瘫痪患儿肌张力的影响[J].中国康复理论与实践，2013， 19（8）：771-774.
[19] 李林，姜云，徐金贵，等.五行音乐合中药治疗围绝经期抑郁症的临床观察[J].中华中医药杂志，2011，26（11）：2578-2760.
[20] 艾春启，陈生梅，谢贵文.五行音乐疗法对抑郁症的疗效观察[J].湖北中医杂志，2011，33（2）： 15-16. |
|
|
|
