多器官功能障碍综合征患者血流动力学和炎症介质清除效能及预后影响分析

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Abstract Objective To study the effect of continuous veno-venous hemofiltration (CVVH) on patients with multiple organ dysfunction syndrome (MODS) after wasp sting poisoning. Methods The clinical data of 48 cases with MODS after wasp sting poisoning in Center Hospital of Jiangjin District from October 2010 to October 2016 were retrospectively analyzed. They were divided into experimental group (24 cases) and control group (24 cases) according to the hemopurification program. All the patients were treated by blood perfusion (HP); then the experimental group was treated by CVVH, and the control group was treated by intermittent hemodialysis (IHD). One week after treatment, the curative effect and prognosis of the two groups were evaluated and compared. Results After treatment, the scores of APACHE II and MODS in the experimental group were lower than those in the control group (P < 0.05). The change of hemodynamic indexes in the experimental group was better than that in the control group (P < 0.05). The IL-6 level in the experimental group was lower than that in the control group (P < 0.05). The SOFA score in the experimental group was lower than that in the control group (P < 0.05). Conclusion CVVH can remarkably remove the inflammatory media, improve the hemodynamic level and prognosis of patients with MODS after wasp sting poisoning, which is worthy of clinical application.

Key words： Continuous veno-venous hemofiltration Wasp Multiple organ dysfunction syndrome

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	YANG Jun LI Bin▲

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YANG Jun LI Bin▲. The analysis of the efficacy and prognosis of hemodynamic and inflammatory mediators in patients with multiple dysfunction syndrome after wasp stinging poisoning treated by continuous veno-venous hemofiltration[J]. 中国医药导报, 2017, 14(25): 23-25,37.

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http://www.yiyaodaobao.com.cn/EN/ OR http://www.yiyaodaobao.com.cn/EN/Y2017/V14/I25/23

[1] 王晓明，孙燕，梁衍，等.重症蜂蛰伤患者腹膜透析与连续性静——静脉血液滤过治疗的疗效分析[J].中国血液净化，2015，14（4）：219-223.
[2] 黄景荣，计春燕，王景，等.连续性血液净化联合血浆置换治疗老年重症蜂蜇伤致多脏器功能衰竭患者的临床观察[J].实用老年医学，2015（3）：249-250.
[3] 张萍，宋小炜，杨丽南，等.不同蜂种蜂蛰伤致病及蜂毒毒理特点的研究进展[J].西南国防医药，2016，26（4）：447-449.
[4] 麦超，简华刚.大剂量糖皮质激素对重症蜂蜇伤患者预后的影响分析[J].重庆医学，2016，45（25）：3501-3502.
[5] 罗刚，陈仰昆，罗建设，等.全血白细胞计数对黄蜂蜇伤死亡的预测价值[J].中国现代医生，2012，50（6）：49-50.
[6] 胡莹莹，张国秀，刘奎，等.血浆置换联合CVVH治疗蜂蜇伤合并MODS疗效观察[J].实用医学杂志，2016，32（16）：2722-2725.
[7] 陈叙，张春红. MODS的诊断[J].中国实用妇科与产科杂志，2002，18（6）：325-327.
[8] Marshall JC，Cook DJ，Christou NV，et al． Multiple organ dysfunction score：a reliable descriptor of a complex clinical outcome [J]． Crit Care Med，1995，23（10）：1638-1652．
[9] 王小兵. APACHEⅡ评分在急性肾功能衰竭中的应用[J].国际泌尿系统杂志，2003，23（2）：201-204.
[10] 王超，付小萌，赵鹏飞，等. BJ-MODS、APACHEⅡ、SOFA、Marshall-MODS评分系统对MODS患者病情评估价值的比较[J].临床和实验医学杂志，2013，12（22）：1868-1872.
[11] Klijn E，Groeneveld AB，van Genderen ME，et al. Peripheral perfusion index predicts hypotension during fluid withdrawal by continuous veno-venous hemofiltration in critically Ⅲ patients [J]. Blood Purif，2015，40（1）：92-98.
[12] Ouyang SX，Fu J，Liu J T，et al. Heparin-free continuous vena-venous hemofiltration as a veno-venous bypass in inferior vena cava reconstruction [J]. Vascular，2015，24（4）：355-360.
[13] Louise S，Azam NS，Ter WPM，et al. Putative novel mediators of acute kidney injury in critically ill patients：handling by continuous venovenous hemofiltration and effect of anticoagulation modalities [J]. BMC Nephrol，2015，16（1）：1-7.
[14] Ma F，Bai M，Li Y，et al. Continuous venovenous hemofiltration（CVVH）versus conventional treatment for acute severe hypernatremia in critically Ⅲ patients：a retrospective study. [J]. Shock，2015，44（5）：445-451.
[15] 刘振国，王婷，卢晓娥. CVVHDF联合HP治疗蜂蜇伤患者临床生化指标的变化研究[J].现代检验医学杂志，2015，30（5）：115-117.
[16] Janssen PK，Foudraine NA，Burgers DM，et al. Population pharmacokinetics of cefuroxime in criticallyⅢ patients receiving continuous venovenous hemofiltration with regional citrate anticoagulation and a phosphate-containing replacement fluid. [J]. Ther Drug Monit，2016，38（6）：699.
[17] Feng M，Liu Y，Ming B，et al. The reduction rate of serum sodium and mortality in patients undergoing continuous venovenous hemofiltration for acute severe hypernatremia [J]. Am J Med Sci，2016，352（3）：272-279.
[18] 陈洪流，丘瑛，宁宗.早期间断高容量血液滤过对群蜂蜇伤横纹肌溶解患者预后及炎症因子的影响[J].重庆医学，2016，45（29）：4074-4077.
[19] Meulendijks D，Khan S，Koks CH，et al. Baclofen overdose treated with continuous venovenous hemofiltration [J]. Eur J Clin Pharmacol，2015，71（3）：357-361.
[20] 陈传熹，蒋臻，高永莉，等. 926例蜂蛰伤的回顾性分析[J].中国中医急症，2015，24（12）：2103-2105.