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| Analysis on the status and subtypes of HPV infection in 3239 females in Shanghai Pujiang District |
| XU Ya′nan XIAO Shijin LIU Wei▲ |
| Department of Gynaecology and Obstetrics, South Campus of Renji Hospital, School of Medicine, Shanghai Jiaotong University, Shanghai 201112, China |
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Abstract Objective To investigate the infection status and genotype distribution of human papilloma virus (HPV) infection in Shanghai Pujiang District, and to provide a theoretical basis for the prevention of HPV infection and control of cervical lesions. Methods The detection results of cervical cytology screening for 3239 females in South Campus, Renji Hospital, School of Medicine, Shanghai Jiaotong University from May 2015 to October 2017 were collected, and the HPV typing data were analysed. Results 3239 cases of women were collected, 589 cases of women were HPV infected (the positive rate of HPV infection were 18.18%). There were 449 cases (76.23%) with single HPV type infection, 106 cases (18.0%) with double HPV subtypes infection and 34 cases (5.77%) with multiple HPV subtypes infection. >50-60 years women had the highest HPV infection rate and high-risk HPV subtype infection rate, the difference was statistically significant (P < 0.01). The most common subtypes were HPV52, 16, 58. Conclusion The HPV infection rate in Pujiang District is high, which mainly caused by single HPV genotypes and high-risk HPV subtypes. The most common subtype was HPV52, 16, 58. It is necessary to lay emphasis on preventing HPV52, 16, 58 infection for females in this area.
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