复方萘普生栓联合间苯三酚在绝经期出血妇女行宫腔镜检查中的应用

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Abstract Objective To investigate the application value of Compound Naproxen Suppository combined with Phloroglucinol during hysteroscopic examination in menopausal bleeding women. Methods A total of 129 cases of menopausal bleeding patients in General Hospital of Xingtai Mining Group from December 2015 to May 2017 were selected. They were randomly divided into observation group and control group I and control group Ⅱ, 43 cases in each group. Hysteroscopy was performed in the three groups. The control group Ⅰ was given Compound Naproxen Suppository, the control group Ⅱ was given Phloroglucinol for injection, and the observation group was given Compound Naproxen Suppositories combined with Phloroglucinol for Injection. The cervical softening and dilatation, pain grading and incidence of adverse reactions were compared among the three groups. Results The cervical softening and dilatation of the observation group was better than that of the control group Ⅰ and the control group Ⅱ, and the difference was statistically significant (P < 0.05). The effect rate of softening and dilatation in the observation group [69.77% (30/43)] was higher than that in the control group Ⅰ and the control group Ⅱ [34.88% (15/43), 39.53% (17/43)], and the difference was statistically significant (P < 0.05). There was no significant difference in cervical softening and dilatation between control group Ⅰ and control group Ⅱ (P > 0.05). There was no significant difference in effecfive rate between the control group Ⅰ and the control group Ⅱ(P > 0.05). The observation group had better pain classification than the control group, and the difference between the two groups was statistically significant (P < 0.05). There was no significant difference in pain classification between the control group I and the control group Ⅱ (P > 0.05). The incidence of skin rash, urticaria, abdominal pain and fever three groups were compared, the difference was not statistically significant (P > 0.05). Conclusion Compound Naproxen Suppository combined with Phloroglucinol is helpful to improve the effective rate of cervical softening and dilatation in hysteroscopic examination of menopausal bleeding. It can effectively alleviate the pain and has certain safety.

Key words： Menopausal bleeding Hysteroscope Compound naproxen suppository Phloroglucinol Cervical softening dilatation Degree of pain

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	REN Wei1 LI Lili1 SHI Huixing1 ZHANG Yongcun1 YUAN Hong1 QIAN Yali1 CUI Fuchun2

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REN Wei1 LI Lili1 SHI Huixing1 ZHANG Yongcun1 YUAN Hong1 QIAN Yali1 CUI Fuchun2. Application of Compound Naproxen Suppository combined with Phloroglucinol during hysteroscopic examination in menopausal bleeding women[J]. 中国医药导报, 2018, 15(21): 78-81.

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http://www.yiyaodaobao.com.cn/EN/ OR http://www.yiyaodaobao.com.cn/EN/Y2018/V15/I21/78

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