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Atypical manifestations and misdiagnosis analysis of children with hypothyroidism |
YU Fei FANG Haining WANG Xiaoxia ZHU Jie SU Hang |
Pediatics Department of Endocrinology and Genetics Metabolism, Maternal and Child Health Care Hospital of Hubei Province, Hubei Province, Wuhan 430071, China |
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Abstract Objective To analyze the atypical manifestations of hypothyroidism in children and long term misdiagnosis, in order to improve the children′s hypothyroidism diagnosis level. Methods The clinical data of 23 cases misdiagnosed children with hypothyroidism in Maternal and Child Health Care Hospital of Hubei Province from August 2013 to December 2017 was collected to review and carry on clinical analysis. Results The main symptoms of 7 cases were long-term anorexia, abdominal distension, constipation and other gastrointestinal symptoms. The main symptoms of 3 cases were severe anemia. The main symptoms of 6 cases were growth retardation, mental retardation. The main symptoms of 7 cases were precocious puberty. Conclusion The manifestation of hypothyroidism is complicated and lacks specificity. Thyroid function test and comprehensive analysis should be carried out in time, that may reduce the rate of misdiagnosis.
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