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Distribution and drug resistance of clinical pathogenic bacteria in our hospital from 2013 to 2015 |
PAN Haiyan XIANG Yonghong LYU Cong |
Guangxi Zhuang Autonomous Region National Hospital Nationnal Hospital Affiliated to Guangxi Medical University, Guangxi Zhuang Autonomous Region, Nanning 530001, China |
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Abstract Objective To analyze the distribution and drug resistance of clinical pathogenic bacteria in Guangxi Zhuang Autonomous Region National Hospital (“our hospital” for short) from 2013 to 2015, and to provide guidance for reasonable clinical drug use. Methods Clinical specimens were collected from hospitalized patients in our hospital from January 2013 to December 2015. Bacterial identification and drug susceptibility testing were performed by VITED-Ⅱ Compact 60. Results A total of 10 453 strains of pathogens were isolated from the three years, among which the gram-negative bacteria were 8948 strains (85.60%), and gram-positive bacterium were 1505 strains (14.40%). The top 5 species were Escherichia coli, Klebsiella pneumonia, Pseudomonas aeruginosa, Acinetobacter baumannii and Coagulase negative staphylococcus aureus. Enterobacteriaceae bacteria and Pseudomonas aeruginosa had high drug sensitive rates to Imipenem, Amikacin, Cefoperazone/Sulbactam and Piperacillin/Tazobactam. Drug resistance of Acinetobacter baumannii to Cefoperazone/Sulbactam was 39.68%, which had higher drug resistance to commonly used antibiotics. Conclusion The main hospital pathogenic bacteria are gram-negative bacteria, and they have high drug resistance rate to common antibacterial, thus reasonable use of antibiotics should be based on the distribution and drug resistance of pathogenic bacteria.
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