非瓣膜性心房颤动脑栓塞患者脑微出血危险因素的Logistic回归分析

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Abstract Objective To analyze the cerebral microbleeds (CMB) risk factors of patients with non-valvular atrial fibrillation and cerebral infarction, and provide guidance for therapeutic schedule for these patients. Methods One hundred and seventeen patients with non-valvular atrial fibrillation and cerebral infarction were enrolled that treated in the Department of Neurology, the Taicang Affiliated Hospital of Soochow University from January 2014 to December 2016, that were divided into CMB group (48 cases) and non-CMB group (69 cases). The demographic characteristics, the common risk factors of stroke and laboratory examination indices were compared between the two groups. Results Among the 117 patients, 48 cases (41%) were detected with CMB; the average age of the CMB group was higher than the non-CMB group (P = 0.002) ; the homocyatein (Hcy) level of the CMB group was higher than the non-CMB group (P = 0.033) ; the low density lipoprotein (LDL-C) of the CMB group was lower than the non-CMB group (P = 0.037); all the differences were statistically significant. Through a Logistic regression analysis, elderly was independently associated with the presence of CMB (P = 0.07, OR = 1.079, 95%CI: 1.021-1.140). Conclusion There is a high prevalence of CMB in patients with non-valvular atrial fibrillation and cerebral infarction and the occurrence of CMB is mainly associated with elderly.

Key words： Atrial fibrillation Cerebral microbleeds Cerebral microbleeds

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	WU Yijie1 SHEN Jiahui1 ZHOU Yi2 ZHAO Heqing3 ZHOU Lihui1▲

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WU Yijie1 SHEN Jiahui1 ZHOU Yi2 ZHAO Heqing3 ZHOU Lihui1▲. Logistic regression analysis of cerebral microbleeds risk factors of patients with non-valvular atrial fibrillation and cerebral infarction[J]. 中国医药导报, 2018, 15(20): 54-57.

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http://www.yiyaodaobao.com.cn/EN/ OR http://www.yiyaodaobao.com.cn/EN/Y2018/V15/I20/54

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