间歇性低氧治疗对急性ST段抬高型心肌梗死患者PCI术后预后的影响

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Abstract Objective To discuss the effect of intermittent hypoxic adaptation on cardiac function and prognosis of patients with ST-segment elevation myocardial infarction after PCI. Methods All the 60 patients with ST-segment elevation myocardial infarction after PCI were treated in the Second Policlinic Directly under the Authority of Hebei Province from January 2016 to May 2017 selected and divided into control group (n = 30) and observation group (n = 30) by random number table. Based on the standard therapy, the observation group was treated by hypoxia interrupted and the control group was treated by regular oxygen therapy, they were treated for 6 months. The heart rate, blood pressure, Hemoglobin, red blood cell, left ventricular ejection fraction (LVEF), left ventricular end systolic dimension (LVDS), left ventricular end diastolic diameter (LVDD) and cardiac events were compared. Results There was no significant difference in heart rate, hemoglobin and RBC count between the two groups (P > 0.05). At one and six months after treatment, systolic blood pressure and LVEF in the observation group were higher than those in the control group, and LVDS and LVDD was lower than those in the control group, with statistical significance difference (P < 0.05). Conclusion Intermittent hypoxic adaptation is beneficial to the repair of damaged myocardial cells. Besides, it can improve the ability of myocardium contraction, promote myocardial microcirculation and inhibit ventricular remodeling after myocardial infarction.

Key words： Intermittent hypoxia ST-segment elevation myocardial infarction Percutaneous coronary intervention Cardiac function

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	LI Ying ZHAO Lihong

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LI Ying ZHAO Lihong. Prognosis effect of intermittent hypoxic adaptation in treating patients with ST-segment elevation myocardial infarction after PCI[J]. 中国医药导报, 2018, 15(20): 50-53.

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http://www.yiyaodaobao.com.cn/EN/ OR http://www.yiyaodaobao.com.cn/EN/Y2018/V15/I20/50

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