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| Clinical efficacy comparation of two different intestine preparation on patients with colorectal cancer underwent elective operation |
| JIN Xianzhen GOU Ya'nan CUI Xijuan LIAO Chunyan QIAO Li′na |
| Department of General Surgery, the First Affiliated Hospital of Xi'an Jiaotong University, Shaanxi Province, Xi′an 710061, China |
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Abstract Object To explore the clinical efficacy of two methods commonly used in preoperative bowel preparation on patients with colorectal cancer. Methods From January 2016 to June 2017, 231 patients with colorectal cancer underwent surgical treatment in Department of General Surgery, the First Affiliated Hospital of Xi'an Jiaotong University were selected and randomly divided into two groups according to the random number table, of which 117 cases in the experimental group and 114 cases in the control group. The experimental group was given compound polyethylene glycol electrolyte for intestinal preparation before operation, while the control group was given soapy water enema. The intestinal cleanliness score, patients' discomfort degree, serum inflammatory index and electrolytes changes, postoperative recovery of intestinal function were observed. Results There were no statistically significant differences in the intestinal cleanliness score, serum leukocyte level potassium and chloride level, postoperative recovery time of intestinal function, postoperative exhaust time, postoperative defecation time and incidence of abdominal infection(P ＞ 0.05). However, the incidence of nausea, abdominal distension or abdominal pain in the experimental group was lower than that of control group in the process of bowel preparation, the serum sodium level in the experimental group was significantly higher than that of control group, with statistically significant differences (P ＜ 0.05). Conclusion Compared with the traditional method of bowel preparation, oral administration with compound polyethylene glycol electrolyte has a more positive effect, and can reduce the degree of discomfort and the incidence of electrolyte imbalance, which is worth promotion and application.
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