短暂性缺血发作7 d内预后的影响因素

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Abstract Objective To explore the factors of affecting the prognosis after transient ischemic attack (TIA) within 7 d. Methods From June 2015 to June 2016, in Xinxiang Central Hospital, 56 patients with TIA and were examined by perfusion-weighted imaging (PWI) and diffusion-weighted imaging (DWI) within 24 hours after onset were selected, there was no cerebral ischemia in DWI images. Meanwhile, the ABCD2 score was applied, the incidence of patients with cerebral infarction within 7 d were followed-up and observed. Results 23 cases (41.1%) had cerebral infarction in 56 patients with TIA within 7 d. The incidence of cerebral infarction in the low risk group of ABCD2 score was lower than that in the middle risk group and the high risk group within 7 d, the middle risk group was lower than the high risk group, the differences were statistically significant (P < 0.05). The incidence of cerebral infarction in the patients with positive MR-PWI examination was significantly higher than that in the negative patients within 7 d, the differences were statistically significant (P < 0.05). Logistic regression analysis showed that PWI positive (OR = 2.998, 95%CI: 1.456-6.172, P = 0.003), ABCD2 score (OR = 3.765, 95%CI: 1.193-11.878, P = 0.024), intracranial vascular stenosis (OR = 4.743, 95%CI: 2.109-10.667, P = 0.000) and atrial fibrillation (OR = 3.051, 95%CI: 1.185-7.855, P = 0.021) were risk factors of cerebral infarction of TIA within 7 d. Conclusion Positive magnetic resonance perfusion imaging, ABCD2 score, intracranial vascular stenosis and atrial fibrillation are important prognostic factors of TIA diseases.

Key words： Perfusion-weighted imaging ABCD2 score Transient ischemic attack Cerebral infarction Prognosis

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	DONG Min1 CHE Zhenyong2▲ ZHAO Jianting2 WANG Huimin2

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DONG Min1 CHE Zhenyong2▲ ZHAO Jianting2 WANG Huimin2. Prognosis factors of transient ischemic attack within 7 days[J]. 中国医药导报, 2018, 15(17): 61-64.

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http://www.yiyaodaobao.com.cn/EN/ OR http://www.yiyaodaobao.com.cn/EN/Y2018/V15/I17/61

[1] Kokubo Y. Epidemiology of transient ischemic attack [J]. Frontiers of Neurology and neuroscience，2014，33：69-81.
[2] Souillard-Scemama R，Tisserand M，Calvet D，et al. An update on brain imaging in transient ischemic attack [J]. Neuro radiol，2015，42：3-11.
[3] 中华医学会神经病学分会.中国急性缺血性脑卒中诊治指南2014[J].中华神经科杂志，2015，48（4）：246-257.
[4] Johnston SC，Rothwell PM，Nguyen-Huynh MN，et al. Validation and refinement of scores to predict very early stroke risk after transient ischaemic attack [J]. Lancet，2007，369（9558）：283-292.
[5] Giles MF，Rothwell PM. Risk of stroke early after transient ischaemic attack： a systematic review and meta-analysis [J]. Lancet Neurol，2007，6（12）：1063-1072.
[6] 短暂性脑缺血发作中国专家共识组.短暂性脑缺血发作与轻型卒中抗血小板治疗中国专家共识（2014年）[J].中华医学杂志，2014，94（27）：2092-2096.
[7] Wardlaw JM，Brazzelli M，Chappell FM，et al. ABCD2 score and secondary stroke prevention： meta-analysis and effect per 1，000 patients triaged [J]. Neurol，2015，85（4）：373-380.
[8] Merwick A，Albers GW，Amarenco P，et al. Addition of brain and carotid imaging to the ABCD2 score to identify patients at early risk of stroke after transient ischaemic attack： a multicentre observational study [J]. Lancet Neurol，2010，9（11）：1060-1069.
[9] Kelly PJ，Albers GW，Chatzikonstantinou A，et al. Validation and comparison of imaging-based scores for prediction of early stroke risk after transient ischaemic attack：a pooled analysis of individual-patient data from cohort studies [J]. Lancet Neurol，2016，15（12）：1238-1247.
[10] F?觟rster A，Gass A，Kern R，et al. Brain imaging in patients with transient ischemic attack：a comparison of computed tomography and magnetic resonance imaging [J]. Eur Neuro，2012，67（3）：136-141.
[11] Simonsen CZ，Madsen MH，Schmitz ML，et al. Sensitivity of diffusion- and perfusion-weighted imaging for diagnosing acute ischemic stroke is 97.5% [J]. Stroke，2015， 46（1）：98-101.
[12] Asdaghi N，Hill MD，Coulter JI，et al. Perfusion MR predicts outcome in high-risk transient ischemic attack/minor stroke：a derivation-validation study [J]. Stroke，2013， 44（9）：2486-2492.
[13] Nah HW，Kwon SU，Kang DW，et al. Diagnostic and prognostic value of multimodal MRI in transient ischemic attack [J]. Inter J Stroke，2014，9（7）：895-901.
[14] Zaharchuk G，Olivot JM，Fischbein NJ，et al. Arterial spin labeling imaging findings in transient ischemic attack patients：comparison with diffusion- and bolus perfusion-weighted imaging [J]. Cerebrovascular Diseases（Basel，Switzerland），2012，34（3）：221-228.
[15] Lee J，Inoue M，Mlynash M，et al. MR perfusion lesions after TIA or minor stroke are associated with new infarction at 7 days [J]. Neurology，2017，88（24）：2254-2259.
[16] 庾建英，刘继新，朱沂，等.灌注加权成像和扩散加权成像对兔早期后循环缺血的对比分析[J].中国神经精神疾病杂志，2011，37（3）：184-187.
[17] Grandin CB，Duprez TP，Smith AM，et al. Which MR-derived perfusion parameters are the best predictors of infarct growth in hyperacute stroke? Comparative study between relative and quantitative measurements [J]. Radiology，2002，223（2）：361-370.
[18] 童彤，姚振威，冯晓源.磁共振弥散和灌注加权成像对短暂性脑缺血发作的评估[J].实用放射学杂志，2012，（2）：170-175，206.
[19] Coutts SB，Modi J，Patel SK，et al. CT/CT angiography and MRI findings predict recurrent stroke after transient ischemic attack and minor stroke：results of the prospective CATCH study [J]. Stroke，2012，43（4）：1013-1017.
[20] Coutts SB，Hill MD，Eliasziw M，et al. Final 2 year results of the vascular imaging of acute stroke for identifying predictors of clinical outcome and recurrent ischemic eveNts （VISION） study [J]. BMC Cardiovasc Disord，2011，11：18.